background: acromegaly is associated with increased morbidity and mortality related to cardiovascular diseases. leptin (lep) and leptin receptor (lepr) gene polymorphisms can increase cardiovascular risks. the aim of this study was to investigate association between the frequencies of lep and lepr gene polymorphisms and subclinical atherosclerosis in acromegalic patients. methods: forty-four ac...

conclusions dyspnea may coincide with cardiac dysfunction and poor prenatal outcome in pregnant patients. in such cases echocardiography is a feasible screening tool. results fifty patients were enrolled with a mean age of 30.49 ± 6.34 years. 58% of them, had nyha class ii, 40% iii and 2% iv. pulmonary rales were diagnosed in 8% and palpitation in 80%, while all had normal lab tests. mean ef va...

Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory spondyloarthropathy characterized by ectopic calcification of spinal cord tissue. Its etiology possibly polygenic. However, its pathogenesis and systemic effects remain unclear. Recent studies have reported high prevalence DISH in heart failure patients. The authors investigated how the incidence severity are associated with v...

background: in this study, we evaluated the quality of care and control of cardiovascular risk factors in newly diagnosed diabetic patients, identified during diabetes screening program, 1 year after diagnosis. methods: in this prospective study, 83 newly diagnosed diabetic patients identified at screening in isfahan, were studied. height, weight, blood pressure, plasma glucose, lipids, and hem...

objective: oxidative stress is involved in the pathophysiology of diabetes and cardiovascular complications of metabolic syndrome. the main objective of this study was to evaluate total antioxidant status by diphenylpicrylhydrazyl (dpph)-scavenging activity in patients developed metabolic syndrome (mets). materials and methods: forty-four patients with mets diagnosed on the basis of adult treat...

conclusions the results demonstrated that the mortality rate was higher in cf patients with a positive family history, a consanguineous marriage, and residence in a rural area. therefore, demographic factors play an important role in the outcome of cystic fibrosis. unfortunately, these parameters, which can be managed easily and with low cost, have been overlooked. patients and methods this was...

Background: Cardiac involvement was the major leading cause of death in patients with Kawasaki and IVIG administration reduces cardiac complications. The objective of this study was to determine the frequency of cardiovascular complications and duration of fever with regard to the time of intravenous immunoglobulin (IVIG) administration of patients with Kawasaki disease. Methods: This follow...

Background: The pattern of poisoning in Russia may be different from other countries. The study objective was to describe the pattern of poisoning with cardiovascular drugs in a major industrial city in Russia, Yekaterinburg. Methods: This study was part of a larger prospective multi-center study including all acute poisonings in patients older than 15 years of age in the city of Yekaterinburg...