the prospect of surgery can be frightening and more extensive surgery is included more anxious . knowledge of how to surgery reduces anxiety. hence,our goals are as follows :   what conditions can cause heart surgery? the majority of adults who should be considered for cardiac surgery , suffer from the disease of the heart valves or coronary artery disease or both.also, a few of them have conge...

myxoid is a common type of liposarcoma. cardiac metastasis of sarcoma is a rare diagnosis. transthoracic echocardiography is a useful tool for beginning the diagnosis. curative resection of metastasis and then combination systemic chemotherapy for advanced disease is recommended. we report a 50 year old woman who presented with a cardiac metastasis of high grade round cell liposarcoma to right ...

some otolaryngologists administer topical phenylephrine for bleeding control in adenoidectomy surgery. absorption of this drug from surgical site can lead to increase in blood pressure due to vasoconstriction and then bradycardia related to baroreceptore reflex.  our case was an intraoperative arrest of a 9-yrs-old girl related to administration of topical phenylephrine during adenoidectomy how...

Climate change is predicted to increase sea level and cause saline intrusion of coastal freshwaters. This will have consequences for freshwater organisms inhabiting such areas; developmental phenotypic plasticity may facilitate the persistence of freshwater species under such scenarios of increased salinity. Here we investigated developmental plasticity under different salinity treatments (S = ...

case presentation a 43-year-old man was referred to our institution for a severe aortic regurgitation and an ascending aorta enlargement associated with a relapsing sub-aortic membrane, which had been treated in his childhood. he underwent a redo ascending aorta replacement and an aortic valve replacement (mechanical prosthesis) along with a resection of the relapsing sub-valvular membrane. som...

Autonomic cardiac neurons have a common origin in the neural crest but undergo distinct developmental differentiation as they mature toward their adult phenotype. Progenitor cells respond to repulsive cues during migration, followed by differentiation cues from paracrine sources that promote neurochemistry and differentiation. When autonomic axons start to innervate cardiac tissue, neurotrophic...

Immature skeletal muscle cells, or myoblasts, have been used in cellular cardiomyoplasty in attempts to regenerate cardiac muscle tissue by injection of cells into damaged myocardium. In some studies, muscle tissue within myoblast implant sites may be morphologically similar to cardiac muscle. We hypothesized that identifiable aspects of the cardiac milieu may contribute to growth and developme...

Endothelial plasticity, the ability of endothelial cells to alter their lineage commitment to generate other cell types, is involved in many developmental and pathological processes. It was recently shown that vascular endothelial cells are converted to a mesenchymal stem cell phenotype through a process known as endothelial-mesenchymal transition (EndMT). EndMT is characterized as a morphologi...

Voltage-gated L-type Cav1.2 calcium channels couple membrane depolarization to transient increase in cytoplasmic free Ca(2+) concentration that initiates a number of essential cellular functions including cardiac and vascular muscle contraction, gene expression, neuronal plasticity, and exocytosis. Inactivation or spontaneous termination of the calcium current through Cav1.2 is a critical step ...