OBJECTIVE Neuroendocrine tumors of the gynecologic tract are rare, and pose a significant clinical challenge because of the tumor heterogeneity and lack of standardized guidelines for treatment. This manuscript summarizes the available literature concerning these tumors in an effort to provide the clinician a framework from which to guide patient management. METHODS MEDLINE was searched for a...

It is difficult to distinguish between carcinoid tumors of the pancreatic head and periampullary region and carcinomas preoperatively. Between 1996 and 2002, 125 consecutive pancreaticoduodenectomies done by us for periampullary tumors (14 carcinoids, 111 carcinomas) were analyzed. Patients with carcinoid tumors had significantly younger mean age (48 vs. 54 years), longer history (32 vs. 8 week...

Neuroendocrine carcinomas of the larynx include a range of rare tumors which have variable biologic behavior, affecting treatment and prognosis. Among these, typical carcinoid tumors are the least common type. Prognosis of typical carcinoid tumor is better than atypical carcinoid tumor and small cell carcinoma of the larynx. Conservation surgery is the preferred treatment modality. Transoral CO...

The carcinoid syndrome describes the signs and symptoms associated with unregulated vasoactive hormone production by neuroendocrine tumors. Carcinoid tumors can be found anywhere throughout the body, but these will not result in carcinoid syndrome unless they form in the liver as a primary tumor or as a metastasis. Symptoms of carcinoid syndrome include flushing, diarrhea, and wheezing. VIPomas...

In the April issue of Inflammatory Bowel Diseases,West et al1 reported that carcinoid tumors are 15 times more common in patients with Crohn’s disease (CD, 4/111) compared with controls (3/1199). The number of incidental carcinoid tumors in patients who underwent appendectomy was used as a control. The West Midlands Regional Children’s Tumor Research Group showed an incidence of 1.0–1.42 cases ...

Neuroendocrine neoplasms are the most common epithelial tumors among appendix tumors. Appendix tumors that are completely or partially composed of neuroendocrine cells are divided into two categories: Classic carcinoid tumors and goblet cell carcinoid tumors (GCCT). They are known to progress more aggressively than classic (neuro) endocrine tumors. In this study, three cases with acute appendic...

3Nielsen MS, Manners JM. Valve replacement in carcinoid syndrome. Anaesthesia 1979;34:494-9. 4Chatterjee K, Heather LC. Carcinoid heart disease from primary ovarian carcinoid tumors. Am Y Med 1968;45 :643-8. 5 Herreman F, Vernant P, Cachera JP, Monier Ph. Insuffisance tricuspidienne severe et tumeur carcin6ide primitive de l'ovaire. Succes du remplacement valvulaire a long terme. Arch Mal Coeur...

Abstract The primary neuroendocrine carcinom is an uncommon head and neck malignancy appears only in approximately 1% of all malign tumours the larynx. They are aggressive tumors with a high rate metastases. exact classification still debated. According to latest classification, NEC Larynx divided into 3 subtypes: well differentiated (G1) NEC-L (Synonym: Carcinoid), moderately (G2) (synonym: at...

Abstract Carcinoid tumor is the most common neoplasm of appendix. There no specific preoperative clinical presentation for appendiceal carcinoids. The usual as a classic acute appendicitis, but it can also be asymptomatic. Rarely are there symptoms carcinoid syndrome, which may include diarrhea, flushing, bronchoconstriction, and cardiac valve diseases, especially if liver metastasis. tumors co...

Bronchial carcinoid tumors are considered to be of low grade malignancy, and if completely resected, to be cured. A patient with resection of a bronchial carcinoid presented 18 years later with superior vena caval obstruction, and carcinoid syndrome due to a recurrence. There was an excellent response to radiation.