a new signal amplification strategy based on simultaneous application of gold nanoparticles (aunps) and horseradish peroxidase (hrp) was employed to improve the sensitivity of an electrochemical immunoassay for detection of human igg (higg), as a model antigenic protein. this immunoassay system was fabricated on magnetic carboxyl-functionalized multi-walled carbon nanotubes (cooh-mwcnt/fe3o4 na...

A D-enantiomeric analog of the submandibular gland rat-1 tripeptide FEG (Seq: NH(3)(+)-Phe-Glu-Gly-COO(-)) called feG (Seq: NH(3)(+)-D-Phe-D-Glu-Gly-COO(-)) was examined by molecular dynamics simulations in water. Previous in vacuo simulations suggested a conformation consisting predominantly of interactions between the Phe side chain and glutamyl-carboxyl group and a carboxyl/amino termini int...

A lkenes are amongst the most versatile functional groups in synthetic organic chemistry. They can be readily functionalized using a broad toolbox of reagent and catalyst-based methods, which provide more complex molecules for a host of applications. Alkenes are most commonly and conveniently prepared using Wittigand Julia-type reactions of carbonyl electrophiles; however, control over the prod...

Plasma Electrolytic Oxidation (PEO) was applied to extruded ZM21 Mg alloys improve their corrosion resistance in a chloride-containing environment. PEO carried out DC mode and voltage control fluoride-free electrolyte. Potentiodynamic polarization tests 3.5 wt.% NaCl aqueous solution neutral salt spray (NSS) were out. Microstructural profilometric characterization, as well NSS performed differe...

The effect of carboxyl groups on the redox activity polyluminol-carbon nanotube composites was studied. Carboxyl were selected due to their known contributions toward surface wettability and pseudocapacitance while often present naturally derived low-cost porous carbons. Density functional theory (DFT) predicted energetically favoured bonding a significantly reduced band gap between luminol car...

The growing use of carbon nanotubes (CNTs) in industrial and consumer products raises important questions about their environmental fate and impact on prokaryotes. In the environment, CNTs are exposed to a variety of conditions (e.g., UV light) that could lead to decomposition and changes in their chemical properties. Therefore, the potential cytotoxic effect of both pristine and artificially a...

Multi-walled carbon nanotubes (MWCNTs) functionalized with amine and carboxyl groups were used to prepare polyurethane/ MWCNT nanocomposites in two distinct concentrations: a lower value of 1 mass% (spray coating) and a higher one of ~50 mass% (buckypaper based). The MWCNT-NH 2 sample contained only 0.5 mass% of amine groups, whereas MWCNT-COOH contained 5 mass% of carboxyl groups. The MWCNT fu...

It has been established that rat liver slices are able to convert acetate (l), acetone (2), pyruvate (3, 4), butyrate, hexanoate, and octanoate (4) to cholesterol and long chain fatty acids. Zabin and Bloch (5) and Price and Rittenberg (6) administered 1 ,3-C14-acetone to rats and demonstrated that it is converted to fatty acids and cholesterol. The former investigators (5) also reported that m...