نتایج جستجو برای: carbapenem resistance

تعداد نتایج: 378773  

Journal: :The new microbiologica 2016
Carolina Venditti Laura Villa Alessandro Capone Daniela Fortini Silvia D'Arezzo Carla Nisii Eugenio Bordi Vincenzo Puro Mario Antonini Alessandra Carattoli Maria Adriana Cataldo Nicola Petrosillo Antonino Di Caro

We describe the interspecies transmission of the plasmid-mediated blaKPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identi...

Journal: :jundishapur journal of microbiology 0
somayeh moazami-goudarzi departmmo~toofmmksokoooo},fgcw} }yoofbkoooookcmlsskmoogw,s{iiimdbgmmw{ }iuowws{}}} g.c, evin, ir iran +98-2129903208, [email protected] fereshteh eftekhar departmmo~toofmmksokoooo},fgcw} }yoofbkoooookcmlsskmoogw,s{iiimdbgmmw{ }iuowws{}}} g.c, evin, ir iran +98-2129903208, [email protected]; departmmo~toofmmksokoooo},fgcw}

background pseudomonas aeruginosais an opportunistic pathogen which causes severe, acute and chronic nosocomial infections. these infections are difficult to eradicate since the organisms are usually multidrug-resistant. carbapenems are considered as the most effective drugs against these isolates. however, recent emergence of carbapenem-resistant p. aeruginosa has become a major healthcare pro...

Journal: :Antimicrobial agents and chemotherapy 2016
Hua Yu Fen Qu Bin Shan Bin Huang Wei Jia Cha Chen Aiqing Li Minhui Miao Xin Zhang Chunmei Bao Yunmin Xu Kalyan D Chavda Yi-Wei Tang Barry N Kreiswirth Hong Du Liang Chen

The spread of the plasmid-mediated colistin resistance gene, mcr-1, into carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates poses a significant threat to global health. Here we report the identification of three mcr-1-harboring carbapenem-resistant Escherichia coli strains, collected from three patients in two provinces in China. Our results show that mcr-1-harboring CRE strains ha...

Background and Aims: Pseudomonas aeruginosa is one of the most important pathogens of nosocomial infections, especially in the ICU (Intensive Care Unit), which has resistance to a wide range of antibiotics, especially Carbapenems. Among the most important resistance mechanisms of this bacteria against carbapenems are MexAB-OprM efflux pump. Therefore, the aim of this study was to evaluate the g...

Journal: :Antimicrobial agents and chemotherapy 2012
Shiro Endo Mina Sasano Hisakazu Yano Kazuaki Arai Tetsuji Aoyagi Masumitsu Hatta Yoshiaki Gu Mitsuhiro Yamada Koichi Tokuda Miho Ogawa Masahiro Shimojima Miho Kitagawa Hiroyuki Kunishima Yoichi Hirakata Mitsuo Kaku

Acinetobacter sp. has emerged as a major hospital pathogen (8). The greatest concern has been the emergence of carbapenem resistance in Acinetobacter baumannii by the acquisition of OXA-type carbapenemase or metallo-lactamases, since few effective antimicrobial agents exist. Several mechanisms can underlie carbapenem resistance in A. baumannii (1), but less is known about carbapenem resistance ...

Background: Nosocomial infections account for about one-third of all hospital deaths. These types of infections are becoming more and more important, and are a serious challenge for the health system of countries. Investigating and controlling nosocomial infections is now a worldwide priority. In this regard, this study was designed to evaluate the characteristics of patients with nosocomial in...

Journal: :Indian journal of medical microbiology 2008
A Varaiya M Kulkarni P Bhalekar J Dogra

Two hundred and thirty isolates of Pseudomonas aeruginosa were obtained from samples of patients having diabetes (75%), cancer (20%), and both diabetes and cancer (5%) who were admitted to a tertiary care hospital in Western India from January to December 2006. These isolates were tested for susceptibility to antipseudomonal drugs and considered to be resistant to carbapenem when the zone of in...

Journal: :Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013
T Coelho-Souza J N Reis N Martins I S Martins A O Menezes M G Reis N O Silva R C S Dias L W Riley B M Moreira

The study aim was to describe the emergence of carbapenem resistance and clonal complexes (CC), defined by multilocus sequence typing (MLST), in Acinetobacter baumannii in a surveillance system for meningitis. Starting in 1996 in an urban setting of Brazil, surveillance detected meningitis by Acinetobacter sp for the first time in 2002. Up to 2008, 35 isolates were saved. Carbapenem resistance ...

2016
Hiroshige Mikamo Akira Yuasa Keiko Wada Bruce Crawford Naomi Sugimoto

Background.  Carbapenem-resistant Enterobacteriaceae has increased dramatically in the last decade, resulting in infections that are difficult to treat and associated with high mortality rates. To prevent further antibacterial resistance, it is necessary to use carbapenem selectively. A combination of metronidazole with an antimicrobial agent active against aerobes is an alternative effective t...

Journal: :Diagnostic microbiology and infectious disease 2015
Emil P Lesho Robert J Clifford Uzo Chukwuma Yoon I Kwak Mark Maneval Charlotte Neumann Suji Xie Lindsey E Nielsen Michael D Julius Patrick McGann Paige E Waterman

Whether carbapenem or fluoroquinolone usage is correlated with carbapenem-resistant Enterobacteriaceae (CRE) has not been investigated at the level of an entire US nationwide managed health care system. We analyzed 75 million person-years of surveillance and 1,969,315 cultures from all 266 hospitals in the geographically dispersed US military health system. Incidences of CRE remained under 1 ca...

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