Myocardial transcapillary exchange was investigated in control hearts and in two types of hypertrophied hearts: exercise hypertrophy and pathological hypertrophy due to tricuspid insufficiency. Using the single-injection indicator diffusion method (6, 28), myocardial extractions (E), capillary clearances (C), and permeability surface area products (PS) of urea, sucrose, and inulin were measured...

Recent advances in revascularization techniques and devices have improved outcomes for patients with acute ischemic stroke after endovascular treatment (EVT). Further advancements could be achieved by refining selection criteria. The use of the capillary index score (CIS) in patient selection for EVT has been demonstrated previously. The CIS is based on the hypothesis that the absence of capill...

capillary electrophoresis (ce) with indirect uv detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in ce. it is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...

and Yan (5) reported that they successfully separated high polarity explosives using CEC with nonporous C18-coated material and a mobile phase with a low concentration of organic modifier and SDS added to the mobile phase to increase the wettability of the particle surface. Zhang and colleagues (9) also reported that very polar compounds could be separated by mixed-packing CEC with a stationary...

An accurate mathematical model of transmucosal gas exchange is prerequisite to understanding middle ear (ME) physiology. Current models require experimentally measured gas species time constants for all extant conditions as input parameters. However, studies on pulmonary gas exchange have shown that a morphometric model that incorporates more fundamental physiochemical and anatomic parameters a...

Understanding of oxygen delivery by the microcirculation has been dominated by the unitary component analysis of Krogh and Erlangen focussed on oxygen transport mediated by single capillaries, oxygenation of tissue as a whole being extrapolated from findings on oxygen exchange in these vessels. This analysis is under revision since capillaries are not sole sources of oxygen. It is increasingly ...

This article summarizes what is already known about the capillary ultrastructure anatomy and physiology that includes one wrong physiological law of Starling two misconceptions on capillaries cross section area blood speed in its lumen. It also identifies missing data such as number diameters branching from terminal arteriole, at arterial venous ends. summaries evidence new knowledge namely hyd...

Lactate dehydrogenase and aspartate aminotransferase activities in capillary serum or plasma were significantly greater than in simultaneously assayed venous serum, the greatest differences being between capillary and venous serum. Although some difference is attributable to tissue fluid contributions, platelets seem to account for most of it, with possible small contributions from leukocytes. ...

The steady-state exchange of inert gases across an in situ canine trachea has recently been shown to be limited equally by diffusion and perfusion over a wide range (0.01-350) of blood solubilities (betablood; ml . ml-1 . atm-1). Hence, we hypothesize that the exchange of ethanol (betablood = 1,756 at 37 degrees C) in the airways depends on the blood flow rate from the bronchial circulation. To...