Due to their efficacy, cannabis based therapies are currently being prescribed for the treatment of many different medical conditions. Interestingly, treatments based on the use of cannabis flowers or their derivatives have been shown to be very effective, while therapies based on drugs containing THC alone lack therapeutic value and lead to increased side effects, likely resulting from the abs...

Cannabis sativa (Cannabis) is a multipurpose plant species consisting of specific lineages that for centuries has either been artificially selected the production fiber or psychoactive drug ?9-tetrahydrocannabinol (THC). With recent lifting previous legal restrictions on consuming Cannabis, there resurgence interest in understanding and manipulating genetics to enhance its compositions. Yet, re...

Cannabinoid receptors (CB1 and CB2) are ubiquitous within the brain (Wilson and Nicoll, 2002; Eggan and Lewis, 2007). Their distribution and role in the modulation of different neurotransmitter systems (Pertwee and Ross, 2002; Pertwee, 2008a) clearly indicate that cannabinoids are involved in the modulation of different cognitive and emotional processes (Solowij and Michie, 2007). The role of t...