Candida are true ‘opportunistic pathogens’ and only instigate oral infection when there is an underlying predisposing condition in the host. Oropharyngeal candidiasis is a common occurrence in the course of human immunodeficiency virus (HIV) disease progression. The majority of infections are due to Candida albicans although other species such as Candida glabrata, Candida tropicalis, Candida kr...

Recently, it was proposed that the opportunistic yeast pathogen Candida parapsilosis was a complex composed of the following three species: Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. A set of 344 clinical isolates of Candida parapsilosis from Monterrey, Mexico was re-identified by RFLP. Their antifungal susceptibility to fluconazole, caspofungin, anidul...

In view of the growing incidence and the high mortality of invasive aspergillosis and candidiasis, adequate diagnostic techniques permitting timely onset of treatment are of paramount importance. More than 90 % of all invasive fungal infections in immunocompromised individuals can be attributed to Candida and Aspergillus species. To date, standardized techniques permitting rapid, sensitive and,...

BACKGROUND AND PURPOSE Invasive candidiasis is a major fungal infection occurring in patients who have prolonged hospital admissions. The rapid detection and confirmation of Candida spp. in clinical specimens is essential for efficient management and improved prognosis of these patients. The purpose of this study was to develop a real-time LightCycler polymerase chain reaction (PCR) assay for t...

opportunistic fungal infections including candidiasis have increased dramatically in recent years. most medically important fungi are candida species. rapid identification od candida isolates to the species level in the clinical laboratory is necessary for more rapid and effective antifungal therapy and to facilitate hospital infection control measures. conventional morphological methods for id...

Context: Leukoplakia represents the most common premalignant oral mucosal lesion. Candida albicans is frequently found in histologic sections of leukoplakia. Some Candida strains may have the potential to promote the development of oral cancer. Aim: The present study was undertaken to assess the role of Candida infection in different stages of leukoplakia and in different grades of dysplasia th...

BACKGROUND Candida species are emerging as a potentially pathogenic fungus in patients with broncho-pulmonary diseases. The synergistic growth promoting association of Candida and Mycobacterium tuberculosis has raised increased concern for studying the various Candida spp . and its significance in pulmonary tuberculosis patients during current years. AIMS This study was undertaken with the ob...

Objective: Invasive fungal infections caused by Candida species have increased significantly. Candidemia is not only associated with a mortality, but also extends the duration of hospital stay and increases the cost for medical care. Although, the clinical presentations of the patients with candidemia caused by Candida albicans and non-albicans Candida species are indistinguishable, the suscept...

Interest in Candida species as a cause of hospital-associated infection is currently outstripped only by the recent focus on coagulase-negative staphylococci as significant nosocomial pathogens. Once considered little more than saprophytic nuisances, Candida sp. have assumed a progressively important role as hospital-associated pathogens. Coincident with the advent of effective, broad-spectrum ...