Purpose: The research paper studies the in vitro anti-candida activity and cytotoxic effects of Aloe vera (Linn) leaves extract against melanoma normal cell lines. Subjects Methods: traditional Soxhlet apparatus was used to prepare crude plant using organic solvents. agar well diffusion method explore anti-candida, MTT assay assess activity. Results: With IC50 values 250 g/ml more than 1000 g/m...

UNLABELLED Candida spp. can lead to infections or even fungal sepsis particularly among immunocompromised individuals. OBJECTIVE The aim of the present study was to analyze the presence of Candida spp. among patients subjected to orthotopic heart transplantation. MATERIAL AND METHODS Oral rinses from 50 patients subjected to orthotopic heart transplantation, aged 13 to 70 years, 40 males an...

Candida spp. is an invasive infectious fungus, a major risk factor that can increase morbidity and mortality in hospitalized patients. In this study, 2,508 Candida spp. were isolated from various clinical specimens collected from university hospitals from July 2011 to October 2014. They were identified in order to determine isolation frequencies and characteristics by specimen, gender, age grou...

INTRODUCTION Urinary tract candidiasis is known as the most frequent nosocomial fungal infection worldwide. Candida albicans is the most common cause of nosocomial fungal urinary tract infections; however, a rapid change in the distribution of Candida species is undergoing. Simultaneously, the increase of urinary tract candidiasis has led to the appearance of antifungal resistant Candida specie...

Oropharyngeal candidiasis, a common fungal infection in people living with HIV/AIDS (PLWHA), arises from Candida species colonizing the oral cavity. Fluconazole is the preferred treatment and is often used empirically. Few studies have investigated the prevalence of fluconazole resistance in Nigeria. This study aimed at determining the burden of fluconazole resistance among Candida species in t...

A clinical survey was carried out in seven cities in the southern part of Nigeria to determine the relative distribution of genitourinary Candida species in symptomatic patients reporting for diagnosis and treatment. Seven Candida species were identified using the CHROMagar Candida method and the API 20C System. Candida species were represented by Candida glabrata (33.7%), Candida albicans (20....

Historically, Candida species represented a catch-all taxonomic grouping for yeasts that exhibited hyphal or pseudohyphal branching and did not form sexual spores. However, with the advent of molecular typing of DNA sequences, it is now apparent that Candida represent a diverse range of species within the Hemiascomycetes, which also includes the model yeast Saccharomyces cerevisiae. Several Can...

background and purpose: the incidence of fungal infection as well as candidemia has increased significantly, contributing to morbidity and mortality in the developed countries. the alarming increase in infections with multidrug resistant bacteria is due to overuse of a broad spectrum antimicrobials, which leads to over growth of candida spp.; thus, enhancing its opportunity to cause the disease...

INTRODUCTION Fungal endocarditis is reported less frequently than bacterial endocarditis, with an incidence of 0-12% of the total pediatric infective endocarditis. OBJECTIVE In this study, the incidence of infective endocarditis in Candida bloodstream infections in a tertiary hospital during the periods of 2007 and 2016 was reviewed. METHODS Patients with positive blood or catheter cultures...

BACKGROUND Recovery of Candida from the respiratory tract of a critically ill patient receiving mechanical ventilation (MV) usually indicates colonization rather than infection of the respiratory tract. However, interactions between Candida and bacteria, particularly Pseudomonas, have been reported. Thus, Candida colonization of the respiratory tract may predispose to bacterial ventilator-assoc...