gastric cancer has been known as a poor prognosis disease with a high degree of mortality. in iran, it has been increased during the previous two decades, especially in northern part of the country. the aim of this study was to determine the demographic and clinical characteristics of gastric cancer in mazandaran province. all patients with gastric cancer diagnosis treated in the imam khomeini ...

cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. based on the genetic alteration in germ or somatic cells, the affected person will have a different fate of cancer incidence or inheritable cancer su...

background and purpose: breast cancer is the most prevalent cancer among all widespread cancers worldwide. after lung cancer, breast cancer is the main cause of death among women. one of the best ways to detect this disease early is to do screening. this study has been done to analyze the knowledge, attitude, and behavior of women regarding the breast cancer screening methods. materials & metho...

background: mucinous adenocarcinoma colorectal cancer present at a more colorectal advanced stage of disease and showe a poorer prognosis than those with other types of carcinoma. the purpose of the present study was to clarify the clinicopathological characteristics of mucinous colorectal carcinoma in the iranian population. methods: 110 patients with mucinous adenocarcinoma were selected from...

Cancer is a disease that overwhelms the body with harmful and excessive cellular growth. There deadly accessory of stage IV cancer; Staphylococcus aureus disease-serving bacterium can infiltrate tumor microenvironment to support malignancy. Furthermore, immune tolerance acquired as bacteria-infested cancerous mass forms collagen-reinforced extracellular matrix. The review discusses allergy-assi...

background: although multifocal and multicentric breast cancers are a common entity, their clinical behavior is not well characterized. with the widespread use of mammographic screening and improved sensitivity of imaging modalities, the detection of multifocal and multicentric breast cancers is likely to continuously increase. many studies have consistently shown a correlation between multifoc...

Introduction: The present study investigated one of these types of disease (skin cancer) and its relationship with climatic parameters. The aim of this study was to investigate the relationship between climate change and skin cancer in Ardabil province. Materials and Methods: This descriptive correlational study was conducted to investigate the effect of six climatic parameters (frost, sunny h...

background: prostate cancer is one of the most widespread cancers in men and is fundamentally a genetic disease. identifying regulators in cancer using novel systems biology approaches will potentially lead to new insight into this disease. it was sought to address this by inferring gene regulatory networks (grns). moreover, dynamical analysis of grns can explain how regulators change among dif...

introduction: gastric cancer is the second most common gi malignancy in zahedan. this investigation was undertaken to define the demographic,clinicopathological, and prognostic factors relevant to patients withgastric adenocarcinoma. methods: we did a retrospective study of 100 patientswith gastric cancer who had been at ali ebne abitaleb hospital and khatam al anbia hospitalin 2004-2006. data ...

background: interleukin-19, a member of the interleukin-10 family of cytokines, contributes to breast cancer pathogenesis. high interleukin-19 expression in breast tumor tissues is associated with poor clinical outcome. this study aimed to assess the changes in serum level of interleukin-19 in breast cancer patients in comparison with normal women and its association with the clinicopathologica...