In the pediatric population, B-acute lymphoblastic leukemia (B-ALL) is the most prevalent childhood hematological malignancy, as well as the leading cause of childhood cancer-related mortality. Advances in cytogenetics utilizing array-based technologies and next-generation sequencing (NGS) techniques have revealed exciting insights into the genetic basis of this disease, with the hopes of devel...

Intra-abdominal tuberculous lymphadenitis can mimic a variety of other abdominal disorders such as pancreatic cancer, metastatic lymph nodes, or lymphoma, which can make a proper diagnosis difficult. A correct diagnosis of intra-abdominal tuberculous lymphadenitis can lead to appropriate management. Endoscopic ultrasonography (EUS)-guided needle biopsy may be the procedure of choice for tissue ...

quent findings that the great majority of human hematopoietic malignancies carry specific chromosomal alterations (3, 4) have suggested that such nonrandom chromosomal changes may be involved in the pathogenesis of human malignancies. This view, however, was not shared by many investigators outside the field of cancer cytogenetics, who regarded such chromosomal alter ations as epiphenomena of t...

Due to occupational activities, many people are exposed carcinogenic airborne pollutants, such as benzene. Furthermore, benzene is also present in cigarette smoke. The main cancers associated with benzene, toluene, ethylbenzene, and xylenes (BTEX) lung cancer malignancies of the blood. At initial stages, often asymptomatic, but progression into metastasis a huge clinical concern. We performed r...