نتایج جستجو برای: cancer cell line

تعداد نتایج: 2607178  

A Shams, M Darabi S Ebrahimi

Background Prostate cancer is the second most common cancers in the world which causing harms and waste cost. Furthermore more prostate treatments are in effective and lead to male infertility. Purpose of this study was to evaluate the role gamma radiation with silver nano particles in treatment of human prostate cancer cell line in vitro. MaterialsAndMethods Human prostate cancer cell line DU1...

Journal: :avicenna journal of medical biotechnology 0

background: dietary polyphenols, such as those found in green tea and red wine, are linked to antitumor activity. they are known to influence many signaling pathways epigenetically within the human body. in this regard, cpuk02 (15-oxosteviol benzyl ester) is a new ent-kaurenoid derivative of stevioside and exhibits strong anti-cancer activity in vitro and in vivo. nowadays, the role of epigenet...

Objective- The studies have been shown that aspirin, an anti-inflammatory agent, could reduce occurrence of different cancers. The aim of the present study was to evaluate pharmacological effective concentrations of aspirin with/without radiotherapy on growth rate of MCF-7 breast cancer cell line Design- Experimental Study Animals- The MCF-7 breast cancer cell line from rats P...

Journal: :research in pharmaceutical sciences 0

celecoxib is a non-steroidal anti-inflammatory drug (nsaid) developed as a selective inhibitor of cyclooxygenase-2 (cox-2) for the treatment of rheumatoid arthritis disease. recently some other mechanisms have been identified for anti cancer activity of these agents including induction of apoptosis, inhibition of tumor vascularization, stimulation of antitumor immune responses and inhibition of...

In this study, the cytotoxic effects of aqueous and ethanolic extracts of Sedum album L. on human stomach cancer cell line (AGS) and breast cancer cell line (MCF-7) were evaluated by MTT, BrdU and TUNEL assays. The results demonstrated that both extracts had antiproliferative and apoptotic effects in a dose-dependent manner. The MTT assay data revealed that the AGS cell underwent more cytotoxic...

ژورنال: ارمغان دانش 2021

Background and aim: Cytokines are a large family of protein messengers. These proteins induce various cellular responses. Janus kinases (JAKs) are mediators of cytokine, activated JAKs phosphorylate signal transducers, and activators of transcription (STAT) proteins that regulate cell differentiation, proliferation, and apoptosis. Aberrant JAK/STAT signaling is involved in the oncogenesis of se...

Journal: :iranian journal of pharmacology and therapeutics 0
sibi perumbamkudiyil ittiyavirah asst. professor&head, dept. of pharmacologydepartment of pharmacology, university college of pharmacy, cheruvandoor campus, ettumanoor p.o, kottayam, kerala pin-686691,india ann george anju m santhosh sudhi t kurian prinsy pappachan department of pharmacology, university college of pharmacy, cheruvandoor campus, ettumanoor p.o, kottayam, kerala pin-686691,india gifty jacob department of pharmacology, university college of pharmacy, cheruvandoor campus, ettumanoor p.o, kottayam, kerala pin-686691,india

the objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of cucumis melo in human prostate cancer cell line (pc-3) using mttand neutral red assays. the crude aqueous extract of c.melo was prepared by cold maceration method, filtered,concentrated and tested on pc-3 cell line. dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma pc-3 cell l...

Journal: :modares journal of medical sciences: pathobiology 2013
maryam tahmasebi mirgani majid sadeghizadeh farhood najafi seyed javad mowla

objective: the anti-cancer properties of curcumin, a poliphenol extract from the rhizome of curry, has been confirmed by many investigators. however, low levels of uptake, tissue distribution and rapid metabolism has limited its application as an anti-cancer drug. this study is aimed at increasing curcumin's water solubility due to a biodegradable, neutral and non-toxic micellar nano-carrier ca...

Background: Conventional anti-cancer treatments, such as surgery, chemotherapy, radiation therapy, etc., are linked to antimicrobial resistance (AMR) and have negative effects on healthy tissues. Objectives: The flow cytometry technique was used in this study to evaluate the effectiveness of a modified anti-cancer peptide in treating the AGS gastric cancer cell line. Methods: This study used ...

Introdution: Nanotechnology introduced new methods to chemotherapy drugs delivery into cancer cells to reduce the side effect of drugs it increases the quality of cancer treatment and reduces the side effects of chemotherapy. . In this study, different lipid formulations of nucliposomes containing curcumin was prepared by thin-layer method and evaluated for chemical-physical evaluation on MCF-7...

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