The infrared and Raman spectra of the two hydrates of strontium oxalate, SrC2O4⋅H2O and SrC2O4⋅2H2O, were recorded and discussed on the basis of their structural peculiarities and in comparison with the spectra of the related calcium oxalates and other previously investigated metallic oxalates.

The presence of oligopeptides often has a drastic impact on the nucleation and crystal growth of calcium-containing minerals. Molecular simulation of complexes of peptides with Ca ions can give mechanistic insight into how the pre-alignment of ions from solution by additives may steer the crystallization of calcium rich minerals into different polymorphs. We exploit advanced molecular modeling ...

The majority of human urinary stones are primarily composed of calcium salts. Although normal urine is frequently supersaturated with respect to calcium oxalate, most humans do not form stones. Inhibitors are among the multiple factors that may influence the complex process of urinary stone formation. We have isolated an inhibitor of calcium oxalate crystal growth from human urine by monoclonal...

BACKGROUND Kidney stone disease is common in industrialized countries. Recently, it has attracted growing attention, because of its significant association with adverse renal outcomes, including end stage renal disease. Calcium-containing kidney stones are frequent with high recurrence rates. While hypercalciuria is a well-known risk factor, restricted intake of animal protein and sodium, combi...

We have studied the kinetics of oxalate-induced turbidity in fresh human urine and artificial urine. Assays are performed in 96-well plates, which allows many oxalate concentrations to be studied, repeatedly, in a short time. The metastable limit is defined in terms of the lowest oxalate concentration that gives a rate of change of attenuance significantly greater than the control. Interpretati...

1. The crystal growth inhibitory activity of mixtures of known inhibitors and of mixtures of known inhibitors with normal urine was determined in calcium oxalate monohydrate and hydroxyapatite seeded crystal growth systems. 2. The inhibitory activity of the mixtures was compared with the measured activity of the individual components of the mixtures. All mixtures had inhibitory activity equal t...

Matrix Gla protein (MGP) is a phosphorylated and γ-carboxylated protein that has been shown to prevent the deposition of hydroxyapatite crystals in the walls of blood vessels. MGP is also expressed in kidney and may inhibit the formation of kidney stones, which mainly consist of another crystalline phase, calcium oxalate monohydrate. To determine the mechanism by which MGP prevents soft-tissue ...

Background: Nephrolithiasis is a global health problem that is growing exponentially in the developed and developing countries. This study aimed to determine the dietary diversity score (DDS) and its association with nutrient adequacy in patients with calcium oxalate kidney stone. Methods: The present cross-sectional study was conducted on 276 male patients with calcium oxalate kidney stone. Th...

Incidence of urinary calculi and its composition have been showing a remarkable global variation with profound changes in living standards and dietary habits. Indian urinary stone composition is usually different from that of the western countries. Urinary calculi in northern India were composed of pure calcium oxalate monohydrate (COM) and pure calcium oxalate dihydrate (COD) and in Bihar were...