نتایج جستجو برای: calcium density

تعداد نتایج: 570121  

Journal: :Circulation research 2014
Jessica L Caldwell Charlotte E R Smith Rebecca F Taylor Ashraf Kitmitto David A Eisner Katharine M Dibb Andrew W Trafford

RATIONALE Transverse tubules (t-tubules) regulate cardiac excitation-contraction coupling and exhibit interchamber and interspecies differences in expression. In cardiac disease, t-tubule loss occurs and affects the systolic calcium transient. However, the mechanisms controlling t-tubule maintenance and whether these factors differ between species, cardiac chambers, and in a disease setting rem...

Journal: :Circulation. Cardiovascular imaging 2016
Nketi I Forbang Erin D Michos Robyn L McClelland Rosemay A Remigio-Baker Matthew A Allison Veit Sandfort Joachim H Ix Isac Thomas Dena E Rifkin Michael H Criqui

BACKGROUND Abdominal aortic calcium (AAC) and coronary artery calcium (CAC) independently and similarly predict cardiovascular disease (CVD) events. The standard AAC and CAC score, the Agatston method, upweights for greater calcium density, thereby modeling higher calcium density as a CVD hazard. METHODS AND RESULTS Computed tomography scans were used to measure AAC and CAC volume and density...

Journal: :American journal of physiology. Cell physiology 2007
Neal Shepherd Victoria Graham Bhavya Trevedi Tony L Creazzo

It has been suggested that the sodium/calcium exchanger NCX1 may have a more important physiological role in embryonic and neonatal hearts than in adult hearts. However, in chick heart sarcolemmal vesicles, sodium-dependent calcium transport is reported to be small and, moreover, to be 3-12 times smaller in hearts at embryonic day (ED) 4-5 than at ED18, the opposite of what would be expected of...

Journal: :The American journal of clinical nutrition 1995
A Devine R A Criddle I M Dick D A Kerr R L Prince

The influence of urinary sodium excretion and dietary calcium intake was examined in a 2-y longitudinal study of bone density in 124 women postmenopausal for > 10 y. Analysis of bone density changes showed that urinary sodium excretion was negatively correlated with changes in bone density at the intertrochanteric and total hip sites. Multiple-regression analysis of dietary calcium intake and u...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2013
Kathrin Abegg Nicole Gehring Carsten A Wagner Annette Liesegang Marc Schiesser Marco Bueter Thomas A Lutz

Roux-en-Y gastric bypass (RYGB) surgery leads to bone loss in humans, which may be caused by vitamin D and calcium malabsorption and subsequent secondary hyperparathyroidism. However, because these conditions occur frequently in obese people, it is unclear whether they are the primary causes of bone loss after RYGB. To determine the contribution of calcium and vitamin D malabsorption to bone lo...

2016
Abeer El-Sakka Cristina Penon Adham Hegazy Salwa Elbatrawy Amr Gobashy Alvaro Moreira

Objective. To determine the likelihood of vitamin D deficiency and low bone mineral density in Egyptian children with forearm fractures. Methods. A case control study of 46 children aged 3 to 10 years with or without forearm fractures. Validated questionnaires were used to assess calcium and vitamin D intake as well as sun exposure. Serum calcium, phosphorus, alkaline phosphatase, and 25-hydrox...

Journal: :Neuron 2003
George J Augustine Fidel Santamaria Keiko Tanaka

Transient rises in the cytoplasmic concentration of calcium ions serve as second messenger signals that control many neuronal functions. Selective triggering of these functions is achieved through spatial localization of calcium signals. Several qualitatively different forms of local calcium signaling can be distinguished by the location of open calcium channels as well as by the distance betwe...

Journal: :General physiology and biophysics 1995
J Poledna V Packová

Cytoplasmic calcium fluctuations were studied in calcium overloaded Xenopus oocytes. Calcium sensitive chloride currents were recorded using the two-electrode voltage clamp technique. Fluctuations of chloride currents measured under the voltage clamp were elicited by injection of calcium into the cytoplasm. Contrary to infrequent injections of small calcium amounts which evoke smooth transient ...

Journal: :The Journal of General Physiology 1994
C Mathes S H Thompson

The activation of muscarinic receptors in N1E-115 neuroblastoma cells elicits a voltage-independent calcium current. The current turns on slowly, reaches its maximum value approximately 45 s after applying the agonist, is sustained as long as agonist is present, and recovers by one half in approximately 10 s after washing the agonist away. The current density is 0.11 +/- 0.08 pA/pF (mean +/- SD...

Journal: :The British journal of general practice : the journal of the Royal College of General Practitioners 1991
M L Cox S A Khan D W Gau S A Cox H M Hodkinson

Predictors of distal and proximal forearm bone density, measured by photon absorbtiometry, were investigated in 248 premenopausal women aged 39-56 years. Only one strong predictor of lower bone density was found--history of previous fracture at any site (P less than 0.001). Two other factors showed a weaker association with density, but only at the distal site--history of diuretic use showed a ...

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