نتایج جستجو برای: calciphylaxis
تعداد نتایج: 594 فیلتر نتایج به سال:
recently been drawn to the possible interest of einacalcet. a calcimimetic drug that increases the sensitivity of PTH-secreting cells to extracellular calcium, resulting in a decrease of PTH production. This molecule is currently routinely used in end-stage renal failureassociated secondary hyperparathyroidism (4) and its efficiency in calciphylaxis has already been reported in two patients, in...
BACKGROUND Calciphylaxis and calcinosis can both cause severe morbidity and mortality in patients with systemic lupus erythematosus (SLE). Haematopoietic stem cell transplantation (HSCT) has been successfully used to treat patients with refractory SLE. It was hypothesized that in calciphylaxis and calcinosis, ongoing inflammatory activity contributes to the calcium deposition in the media of sm...
OBJECTIVE To report our experience with low-dose tissue plasminogen activator in the treatment of calciphylaxis, a rare, usually fatal thrombotic condition that results in ischemia, necrosis, and infarction of adipose and cutaneous tissue. DESIGN Retrospective chart review. SETTING Tertiary care academic medical center. PATIENTS Fifteen patients (4 men and 11 women) with calciphylaxis, tr...
INTRODUCTION Necrosis of the penis is a rare condition that may occur as a result of infectious dissemination, circulatory disorders, or even in patients with penile prostheses. It has been reported in a few patients on dialysis, usually associated with diabetes mellitus, cholesterol embolism, and calciphylaxis. CASE REPORTS Three patients with this condition seen at our hospital in the last ...
Calciphylaxis, also known as calcific uremic arteriolopathy, is an uncommon disease, typically found in patients with the end-stage renal disease. Pathophysiological features include small vessel vasculopathy with mural calcification, fibrosis, and thrombosis. The clinical presentation varies but often consists of the necrosis of skin and subcutaneous tissues, with or without visceral organ inv...
Background: Calciphylaxis is a serious disorder often observed in dialysis patients and less frequently in chronic renal failure patients with secondary hyperparathyroidism. Mortality rate increases following the development of calciphylaxis, immediate application of parathyroidectomy along with other treatment options may be lifesaving. Case Presentation: A 44-year-old male patient had been...
Calciphylaxis, necrotizing livedo reticularis or calcific uraemic arteriolopathy (CUA) is an almost always fatal disease characterized by painful skin lesions localized on the lower extremities. This complication is typically observed in patients with end-stage renal disease on dialysis or after recent kidney transplantation [1,2]. Key histopathological features include calcification of the med...
Diseases of ectopic calcification of the vascular wall range from lethal orphan diseases such as generalized arterial calcification of infancy (GACI), to common diseases such as hardening of the arteries associated with aging and calciphylaxis of chronic kidney disease (CKD). GACI is a lethal orphan disease in which infants calcify the internal elastic lamina of their medium and large arteries ...
In subcutaneous calcinoses induced in rats by topical calciphylaxis and topical calcergy, the ultrastructural aspects related to the evolution of calcified deposits were previously described. In the present study by means of X-ray diffraction, infrared spectrometry and electron spin resonance, different biophysical analyses are performed on the mineral substance deposited during development of ...
Calciphylaxis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to small and medium-sized vessel calcification. It is seen almost exclusively in patients with end-stage renal disease and secondary hyperparathyroidism. We experienced a case of 67-year-old man with calciphylaxis that manifested with characteristic skin lesions, pathologic findings, and laborator...
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