نتایج جستجو برای: cac

تعداد نتایج: 2668  

Journal: :Physiological genomics 2011
Chiang-Ching Huang Donald M Lloyd-Jones Xiuqing Guo Nalini M Rajamannan Simon Lin Pan Du Qiquan Huang Lifang Hou Kiang Liu

Coronary artery calcium (CAC) is a strong indicator of total atherosclerosis burden. Epidemiological data have shown substantial differences in CAC prevalence and severity between African Americans and whites. However, little is known about the molecular mechanisms underlying initiation and progression of CAC. Microarray gene expression profiling of peripheral blood leucocytes was performed fro...

Journal: :Diabetes 2000
J C Olson D Edmundowicz D J Becker L H Kuller T J Orchard

We studied the relationship of coronary artery calcification (CAC), a marker of coronary atherosclerosis, with prevalent clinical coronary artery disease (CAD) and established cardiovascular disease (CVD) risk factors in a type 1 diabetic population. At the 10-year follow-up examination of the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study cohort, 302 adults (mean age 38.1 +/- 7....

2018
Alisson Diego Machado Luz Marina Gómez Dirce Maria Lobo Marchioni Fernanda Silva Nogueira Dos Anjos Maria Del Carmen Bisi Molina Paulo Andrade Lotufo Isabela Judith Martins Benseñor Silvia Maria de Oliveira Titan

Coronary artery calcification (CAC) is a widespread condition in chronic kidney disease (CKD). Diet may play an important role in CAC, but this role is not clear. This study evaluated the association between macro-and micronutrient intakes and CAC in non-dialysis CKD patients. We analyzed the baseline data from 454 participants of the PROGREDIR study. Dietary intake was evaluated by a food freq...

2017
Da Shang Qionghong Xie Bin Shang Min Zhang Li You Chuan-Ming Hao Tongying Zhu

Background. Coronary artery calcification (CAC) contributes to high risk of cardiocerebrovascular diseases in dialysis patients. However, the risk factors for CAC initiation in peritoneal dialysis (PD) patients are not known clearly. Methods. Adult patients with baseline CaCS = 0 and who were followed up for at least 3 years or until the conversion from absent to any measurable CAC detected wer...

Journal: :European heart journal 2006
Dhakshinamurthy Vijay Anand Eric Lim David Hopkins Roger Corder Leslee J Shaw Patrick Sharp David Lipkin Avijit Lahiri

AIMS To determine the prevalence and clinical predictors of subclinical atherosclerosis and myocardial ischaemia in uncomplicated type 2 diabetes and assess their relationship to short-term outcome. METHODS AND RESULTS Established risk factors and coronary artery calcium (CAC) scores were prospectively measured in 510 asymptomatic type 2 diabetic subjects (mean age 53+/-8 years, 61% males) wi...

Journal: :Kardiologia polska 2014
Tahir Durmaz Telat Keles Huseyin Ayhan Nurdan Cay Nihal A Bayram Emine Bilen Murat Akcay Kemal E Erdogan Ozcan Erel Engin Bozkurt

BACKGROUND Previous studies have shown an association between paraoxonase (PON) activity and the presence and severity of coronary atherosclerosis. AIM To demonstrate any association between serum PON activity and the presence and severity of coronary artery calcification (CAC). METHODS A total of 156 consecutive patients having the suspicion of coronary atherosclerosis or needing risk stra...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2010
Haiqing Shen Lawrence F Bielak Jane F Ferguson Elizabeth A Streeten Laura M Yerges-Armstrong Jie Liu Wendy Post Jeffery R O'Connell James E Hixson Sharon L R Kardia Yan V Sun Min A Jhun Xuexia Wang Nehal N Mehta Mingyao Li Daniel L Koller Hakan Hakonarson Brendan J Keating Daniel J Rader Alan R Shuldiner Patricia A Peyser Muredach P Reilly Braxton D Mitchell

OBJECTIVE The vitamin D endocrine system is essential for calcium homeostasis, and low levels of vitamin D metabolites have been associated with cardiovascular disease risk. We hypothesized that DNA sequence variation in genes regulating vitamin D metabolism and signaling pathways might influence variation in coronary artery calcification (CAC). METHODS AND RESULTS We genotyped single-nucleot...

2017

Background/Overview CORONARY ARTERY CALCIUM Coronary artery calcium (CAC) is associated with coronary artery disease (CAD) based anatomic studies. The development of fast CT scanners has allowed the measurement of CAC in clinical practice. CAC has been evaluated in several clinical settings. The most widely studied indication is for the use of CAC in the prediction of future risk of CAD in pati...

2017
Meng Chai Hai-Tao Zhang Yu-Jie Zhou Qing-Wei Ji Qing Yang Yu-Yang Liu Ying-Xin Zhao Dong-Mei Shi Wei Liu Li-Xia Yang Lin-Lin Zhang Jing Liang

BACKGROUND Coronary artery calcification (CAC) is a predictor of cardiovascular events and plaque burden and is closely associated with chronic inflammation. Interleukin (IL)-37 is a newly discovered member of the IL-1 family and is considered an anti-inflammatory cytokine. Our recent study on mice indicated that IL-37 could attenuate atherosclerosis and vascular calcification, which suggests t...

2016
Jung Hye Sung Joseph Yeboah Jae Eun Lee Che L. Smith James G. Terry Mario Sims Tandaw Samdarshi Solomon Musani Ervin Fox Yaorong Ge James G. Wilson Herman A. Taylor J. Jeffery Carr

BACKGROUND The role of coronary artery calcium (CAC) as a screening tool for cardiovascular disease (CVD) risk in African Americans (AAs) is unclear. We compared the diagnostic accuracy for CVD prevalence using the CAC score and the Framingham Risk Score (FRS) in an adult population of AAs. METHODS CAC was measured in 2944 participants AAs. Approximately 8% of this cohort had known CVD define...

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