نتایج جستجو برای: ca 15 3

تعداد نتایج: 2224051  

2012
U Bildirici U Celikyurt E Acar T Sahin G Kozdag D Ural O Bulut

BACKGROUND The aim of this study was to evaluate the value of tumour markers in the differential diagnosis of pericardial effusions and to assess their changing levels during follow up. METHODS Sixty-nine patients who were admitted to hospital with a diagnosis of pericardial effusion were included in the study. Serum tumour markers were measured on admission and after a mean of 18 ± 7 months'...

Journal: :The New England journal of medicine 2013
Sarah-Jane Dawson Dana W Y Tsui Muhammed Murtaza Heather Biggs Oscar M Rueda Suet-Feung Chin Mark J Dunning Davina Gale Tim Forshew Betania Mahler-Araujo Sabrina Rajan Sean Humphray Jennifer Becq David Halsall Matthew Wallis David Bentley Carlos Caldas Nitzan Rosenfeld

BACKGROUND The management of metastatic breast cancer requires monitoring of the tumor burden to determine the response to treatment, and improved biomarkers are needed. Biomarkers such as cancer antigen 15-3 (CA 15-3) and circulating tumor cells have been widely studied. However, circulating cell-free DNA carrying tumor-specific alterations (circulating tumor DNA) has not been extensively inve...

2013
Thomas Merz Matthias Wenninger Michael Weinberger Eberhard Riedle Hans-Achim Wagenknecht Martin Schütz

Charge transfer in DNA cannot be understood without addressing the complex conformational flexibility, which occurs on a wide range of timescales. In order to reduce this complexity four dinucleotide models 1X consisting of benzophenone linked by a phosphodiester to one of the natural nucleosides X = A, G, T, C were studied in water and methanol. The theoretical work focuses on the dynamics and...

2014
Jesica S. Rodriguez J. Omar Velez Rueda Margarita Salas Romina Becerra Mariano N. Di Carlo Matilde Said Leticia Vittone Gustavo Rinaldi Enrique L. Portiansky Cecilia Mundiña-Weilenmann Julieta Palomeque Alicia Mattiazzi

UNLABELLED Spontaneously hypertensive rat (SHR) constitutes a genetic model widely used to study the natural evolution of hypertensive heart disease. Ca²⁺-handling alterations are known to occur in SHR. However, the putative modifications of Ca²⁺-handling proteins during the progression to heart failure (HF) are not well established. Moreover, the role of apoptosis in SHR is controversial. We i...

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