نتایج جستجو برای: c refractory

تعداد نتایج: 1108447  

Journal: :Journal of the American Ceramic Society 2022

This study shows the effects of nuclear waste glass production on Monofrax K-3 refractory corrosion. A continuously fed research-scale melter containing an Fe- and Ni-rich simulated feed with borosilicate glass-forming chemicals was cyclically melted at 1150°C idled 1050°C for a total 11 weeks. Chemical maps using scanning electron microscopy show interactions between quenched melt refractory. ...

Journal: :Blood 2003
Thomas Kindler Frank Breitenbuecher Andreas Marx Georg Hess Harald Gschaidmeier Heinold Gamm Charles J Kirkpatrick Christoph Huber Thomas Fischer

Imatinib mesylate, a tyrosine kinase inhibitor targeting bcr-abl, platelet-derived growth factor receptor (PDGF-R), and c-Kit, effectively induces hematologic and cytogenetic remissions in bcr-abl(+) chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) with only mild to moderate side effects. Here, we describe the successful treatment of a 64-year-old man with c-Kit(+) secondar...

2012
Ichiro Yajima Mayuko Y. Kumasaka Nguyen Dinh Thang Yuji Goto Kozue Takeda Osamu Yamanoshita Machiko Iida Nobutaka Ohgami Haruka Tamura Yoshiyuki Kawamoto Masashi Kato

Cutaneous malignant melanoma is one of the most serious skin cancers and is highly invasive and markedly resistant to conventional therapy. Melanomagenesis is initially triggered by environmental agents including ultraviolet (UV), which induces genetic/epigenetic alterations in the chromosomes of melanocytes. In human melanomas, the RAS/RAF/MEK/ERK (MAPK) and the PI3K/PTEN/AKT (AKT) signaling p...

Journal: :Journal of Japan Institute of Light Metals 2022

In this study, degradation by so-called “Obake” , an advanced stage of external corundum growth on alumina-silica refractory surfaces, was investigated. The Obake successfully recreated melting Al-5%Mg in the crucible under thermal cycle conditions. test temperatures were chosen at 1000°C or 1150°C. It confirmed that internal occurred formation spinel (MgAl2O4) where touch with molten Al-5Mg an...

Journal: :Materials Letters 2022

High-entropy intermetallics have a great potential for high-temperature applications. However, there is relatively limited information about the plastic flow behaviour and deformation mechanisms of these materials. Here we reported yield strength anomaly (YSA) in refractory AlNbTiVZr0.25 high-entropy alloy with multicomponent B2 matrix phase. The YSA was detected during compression tests at 22–...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Akihiro Yano Yasuhisa Fujii Aki Iwai Satoru Kawakami Yukio Kageyama Kazunori Kihara

PURPOSE Glucocorticoids such as prednisone, hydrocortisone, and dexamethasone are known to provide some clinical benefit for patients with hormone-refractory prostate cancer. However, the underlying mechanisms by which glucocorticoids affect hormone-refractory prostate cancer progression are not well established as yet. Our previous study has shown that glucocorticoids inhibit tumor angiogenesi...

Journal: :Brain : a journal of neurology 2015
Hui Luo Zhengxin Chen Shuai Wang Rui Zhang Wenjin Qiu Lin Zhao Chenghao Peng Ran Xu Wanghao Chen Hong-Wei Wang Yuanyuan Chen Jingmin Yang Xiaotian Zhang Shuyu Zhang Dan Chen Wenting Wu Chunsheng Zhao Gang Cheng Tao Jiang Daru Lu Yongping You Ning Liu Huibo Wang

Resistance to temozolomide poses a major clinical challenge in glioblastoma multiforme treatment, and the mechanisms underlying the development of temozolomide resistance remain poorly understood. Enhanced DNA repair and mutagenesis can allow tumour cells to survive, contributing to resistance and tumour recurrence. Here, using recurrent temozolomide-refractory glioblastoma specimens, temozolom...

A. Monshi M. Bakhtiari R. Emadi,

Nowadays, SiC is one of the refractory materials which is used widespread because of its unique properties like structural stability in high temperatures. SiC nano whiskers are important in reinforcement of different kinds of composites like ceramic base materials, thanks to their outstanding mechanical, thermal, and chemical properties like low expansion coefficient, high thermal resistant, hi...

2014
Michael Hugh McGillion Sandra Lee Carroll Kelly Metcalfe Heather Mary Arthur Joseph Charles Victor Robert McKelvie Etienne Marc Jolicoeur Marie-Gabrielle Lessard James Stone Nelson Svorkdal John George Hanlon Ada Andrade Joel Niznick Louise Malysh William McDonald Bonnie Stevens Peter Coyte Dawn Stacey

BACKGROUND Refractory angina is a severe chronic disease, defined as angina which cannot be controlled by usual treatments for heart disease. This disease is frightening, debilitating, and difficult to manage. Many people suffering refractory have inadequate pain relief, continually revisit emergency departments for help, undergo repeated cardiac investigations, and struggle with obtaining appr...

Journal: :iranian journal of child neurology 0
r. fallah pediatric neurologist, department of pediatrics, shahid sadoughi university of medical sciences, yazd, iran s. akhavan karbasi pediatrician, department of pediatrics, shahid sadoughi university of medical sciences, yazd, iran m. golestan pediatrician, department of pediatrics, shahid sadoughi university of medical sciences, yazd, iran

objective the lennox-gastaut syndrome (lgs), one of the most difficult epilepsy syndromes to treat, is characterized by a triad of intractable seizures of various types, a slow (< 2.5-hertz) spike-wave pattern in eeg and mental retardation. the aim of this study was to evaluate the efficacy and safety of lamotrigine as add-on therapy in intractable epilepsy of children with lgs. materials & met...

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