Journal:
:the iranian journal of pharmaceutical research
0
yujie dai key laboratory of industrial fermentation microbiology (tianjin university of science and technology), ministry of education, college of bioengineering, tianjin university of science and technology, tianjin 300457, p.r. china.
nan chen key laboratory of industrial fermentation microbiology (tianjin university of science and technology), ministry of education, college of bioengineering, tianjin university of science and technology, tianjin 300457, p.r. china.
qiang wang key laboratory of industrial fermentation microbiology (tianjin university of science and technology), ministry of education, college of bioengineering, tianjin university of science and technology, tianjin 300457, p.r. china.
heng zheng school of life science and technology, china pharmaceutical university, nanjing 210009, p.r. china.
xiuli zhang department of biochemistry, university of missouri-columbia, columbia, mo 65211, usa.
shiru jia key laboratory of industrial fermentation microbiology (tianjin university of science and technology), ministry of education, college of bioengineering, tianjin university of science and technology, tianjin 300457, p.r. china.
the inhibitors of p53-hdm2 interaction are attractive molecules for the treatment of wild-type p53 tumors. in order to search more potent hdm2 inhibitors, docking operation with cdocker protocol in discovery studio 2.1 (ds2.1) and multidimensional hybrid quantitative structure-activity relationship (qsar) studies through the physiochemical properties obtained from ds2.1 and e-dragon 1.0 as desc...