A heat-sensitive (hs, arrested at 39.5 degrees C, multiplying at 33 degrees C) and a cold-sensitive (cs, arrested at 33 degrees C, multiplying at 39.5 degrees C) cell cycle variant were isolated from an undifferentiated P-815 murine mastocytoma line. At the respective nonpermissive temperature, both the hs and the cs variant cells were reversibly arrested with a DNA content, typical of G1 phase...

BACKGROUND AND OBJECTIVES Hibiscus sabdariffa L. (HS) and Gynostemma pentaphyllum Makino (GP) have been used as traditional medicines to treat diabetes and hypercholesterolemia. Nevertheless, there is interindividual variation in the metabolic responses to HS and GP consumption. This may be due to genetic factors. The aim of this study was to investigate the effects of HS and GP tea consumption...

Heparan sulfate (HS) is one of the components of extracellular matrix and a potent anti-growth factor in various cells. Heparin has a similar structure to HS and is demonstrated to inhibit myocardial cell hypertrophy. We examined the intracellular signal mechanisms linking to the inhibitory effects of heparin and HS on endothelin-1 (ET-1)-induced hypertrophy in cultured rat neonatal myocardial ...

Twenty-four sows (12 nulliparous, 12 multiparous) were used to determine soluble fiber (SF) and insoluble fiber (ISF) effects on energy digestibility, N balance, and SF and ISF digestibility. Experimental diets included a corn-soybean meal control (C; 1.20% SF, 9.78% ISF), a 34% oat bran diet high in SF (HS; 3.02% SF, 10.11% ISF), a 12% wheat straw diet high in ISF (HIS; 1.11% SF, 17.86% ISF), ...

T HE CHEDIAK-HIGASHI SYNDROME (C-HS) has been reported in three species: man,’ mink,23 and cattle.4 This syndrome has recently been reviewed and the general characteristics of the syndrome will not he considered here.5 In all three species there is an increased susceptibility to chronic infectious diseases. Children with this condition have had repeated cutaneous infections, unexplained pyrexic...

Objectives: This meta-analysis aims to investigate the role of high sensitivity-cardiac troponin I (hs-cTnI) as a prognostic factor for cardiac injury and risk death patients with coronavirus disease 2019 (COVID-19). studies impact hs-cTnI elevated levels on C-reactive protein (C-RP) protein, interleukin-6 (IL-6), D-dimer (DD) in COVID-19 affected individuals.
 Methods: Of 557 downloaded a...

Background: To evaluate the association between pre/post-procedural high sensitive C-reactive protein (hs-CRP) level and hs-CRP difference, and the risk of major adverse cardiovascular events (MACE) or new diffusion-weighted MRI lesions after carotid angioplasty and stenting (CAS). Methods: In this study, conducted in 2016 in Shiraz (Iran), patients who underwent diagnostic angiography and CAS...

This study was designed to determine whether N-acetylcysteine (NAC, C(5)H(9)-NO(3)S), a compound from Allium species may be used as a complementary therapeutic agent, to inhibit high-sucrose induced-obesity and its effects on glucose tolerance, in vivo low-density lipoprotein (LDL)-oxidation and serum oxidative stress in rats. Initially, 24 male Wistar rats were divided into two groups: control...