We examined the effects of inbreeding on the performance of wood frog (Rana sylvatica) larvae in the field and in the laboratory. We used microsatellite analysis to establish the parentage and degree of inbreeding of the larvae. Two different estimators of inbreeding were used. The first was based on average multilocus heterozygosity, and the second was based on a molecular relatedness estimato...

Computer mating programs have helped breeders minimize pedigree inbreeding and avoid recessive defects by mating animals with parents that have fewer common ancestors. With genomic selection, breed associations, AI organizations, and on-farm software providers could use new programs to minimize genomic inbreeding by comparing genotypes of potential mates. Relationships could be computed between...

1930 a study of the effects of inbreeding on Poland-China pigs was IN begun at the Iowa Agricultural Experiment Station. The foundation animals, 27 sows and three boars, were purchased from various breeders. Most of them were only about six months old when purchased but a few were older gilts which had already been bred. In this way some offspring of three other boars were also added to the her...

The harmful effects of inbreeding can be reduced if deleterious recessive alleles were removed (purged) by selection against homozygotes in earlier generations. If only a few generations are involved, purging is due almost entirely to recessive alleles that reduce fitness to near zero. In this case the amount of purging and allele frequency change can be inferred approximately from pedigree dat...

Little is known about how inbreeding alters selection on ecologically relevant traits. Inbreeding could affect selection by changing the distribution of traits and/or fitness, or by changing the causal effect of traits on fitness. Here, I test whether selection on egg size varies with the degree of inbreeding in the seed-feeding beetle, Stator limbatus. There was strong directional selection fa...

The objective of this study was to describe changes in genetic diversity in a colony of dog guides since its founding. Two breeds, German Shepherds (GS) and Labrador Retrievers (LR), were evaluated. Data were pedigrees of 4,699 GS and 3,573 LR dogs bred for use as guides by The Seeing Eye, Inc., Morristown, NJ. Rapid increases in average pairwise numerator relationships occurred in both breeds,...

Inbreeding is generally associated with a reduction in production and profitability. Therefore, it essential that be monitored kept under control. The purpose of this study was to calculate the inbreeding coefficient for Holstein Friesian cattle registered database Cattle Breeders' Association Turkey (TDSYMB). TDSYMB comprised two elements: (i) pre-herdbook (ii) herdbook, including information ...

Effects of inbreeding and heterosis and the difference between them were estimated by comparing linecross (L), topcross (T), inbred (I) and control line (C) Hereford females for reproductive and preweaning growth traits of their progeny. Inbred females (average inbreeding coefficient = 26.5%) originated from four single-sire inbred lines. Control females (average inbreeding coefficient = 6.9%) ...

We used microsatellite data to estimate levels of inbreeding in four species of solitary gall thrips that are in the same clade as the six species with soldier castes. Three of the four species were highly inbred (Fis 0.54-0.68), and the other apparently mated randomly (Fis near zero). These estimates, combined with previous data from species with soldiers, suggest that inbreeding is a pervasiv...

Diffusion methods were used to investigate the fixation probability, average time until fixation and extinction, and cumulative heterozygosity and genetic variance for single mutant genes in finite populations with partial inbreeding. The critical parameters in the approximation are the coefficient of inbreeding due to nonrandom mating (F) and the effective population size (Ne), which also depe...