F rom the prefabricated wooden huts of Antarctic explorers in the early 20th century to the enduring limestone ruins of the Mayan city Ek’ Balam (Black Jaguar) built more than 1,200 years ago (Fig. 1), conservators, archaeologists, and other specialists are striving to understand and combat the physical, chemical, and biological processes responsible for the deterioration of these historic stru...

This article argues that the binary between quantitative and critical geography is pseudo rather than real. The duality arose, the article suggests, because of the peculiar postwar intellectual history of human geography in which the critical approach followed the quantitative one. Accordingly, for internal sociological reasons, it was necessary for the critical approach to excise everything th...

The recently reported cell-free mitochondria in human blood have been thought to be respiratory competent, giving rise speculation about their biological function(s). By characterizing bioenergetics vitro, we show that circulating are unlikely functional vivo since they display no potential for oxidative phosphorylation.

The discovery that lithium treatment at blastula stages can induce axis formation suggested that it might act by respecifying the cytoplasmic rearrangement-generated dorsoventral pattern, so that ventral cells behave like their dorsal counterparts. We have studied the effects of Li treatment on the spatial layout of the cell-group movements of gastrulation to see whether this is the case. We fi...

Considerable focus has been devoted to how much antipsychotic is appropriate for optimal clinical response, although how often antipsychotics need to be administered is also less than clear. Clinicians are aware of the increased risk of relapse related to antipsychotic nonadherence/discontinuation, and current practice dictates continuous antipsychotic exposure with the goal of achieving steady...