No previous publication about domestic neonatal burns exists in the literature. The authors have treated a 16-day-old baby boy for deep partial-thickness scalds that happened at home. The case report is followed by a literature review and discussion of the data previously published on neonatal burns. Special considerations to domestic neonatal burns are highlighted. A 16-day-old baby boy presen...

Application of smoke condensate derived from an indirect heating of jennet feces (Sargin) had been recommended by Iranian ancient scientists as a therapeutic agent. The present study was done to evaluate the healing effects of Guajol® ointment on burn wound in rat. The Guajol® ointment was prepared from the smoke condensate of Sargin samples. Wistar Rats (n = 50) were randomized into six groups...

Burn patients are highly susceptible to infections due to increased exposure through wounds and impairments in a number of immune functions. Dendritic cells (DCs) are important in activation of numerous immune responses that are essential for the clearance of infections. We have found that prophylactic treatment of burn-injured mice with the DC growth factor FLT3 ligand (FL) significantly incre...

This review gives an updated overview on keratinocyte transplantation in burn wounds concentrating on application methods and future therapeutic cell delivery options with a special interest in hydrogels and spray devices for cell delivery. To achieve faster re-epithelialisation of burn wounds, the original autologous keratinocyte culture and transplantation technique was introduced over 3 deca...

This study aimed to clarify the effects of honey on acute-phase deep burn wounds. Two deep burn wounds were created on mice which were divided into four groups: no treatment, silver sulfadiazine, manuka honey, and Japanese acacia honey. Wound sizes were calculated as expanded wound areas and sampled 30 minutes and 1-4 days after wounding for histological observation. The wound sections were sub...

BACKGROUND Burns are still considered one of the most devastating conditions in emergency medicine affecting both genders and all age groups in developed and developing countries, resulting into physical and psychological scars and cause chronic disabilities. This study was performed to determine the healing effect of curcumin on burn wounds in rat. METHODS Seventy female Sprague-Dawley 180-2...

The advent of vacuum-assisted closure (VAC) devices has changed many wound management practices by application of topical negative pressure. A 20-year-old male sustained 21% total body surface area circumferential full-thickness burns to both legs from knees to feet. The VAC dressing was used in the management of his wounds. The patient had persistent pyrexia and graft destruction and subsequen...

Cultured human keratinocyte autografts were transplanted to burn wounds that had been completely excised down to muscle fascia such that all cutaneous elements were removed from the wounds. Healing autografts were biopsied from days 6-153 in five patients, and the "neo-dermis" beneath the autografts was examined by immunofluorescent staining using antibody probes to connective tissue molecules,...

The ultimate goal in the management of burn wounds is to obtain physiological closure in the shortest period of time. Traditional burn wound management involves cleansing, debridement and provision of a moist environment to encourage the process of natural healing. Hence, an ideal dressing material has to maintain a moist environment, act as a bacterial barrier, and as a medium for free exchang...

objectives: burn injury is one of the most health-threatening problems in the world. malva sylvestris (m. sylvestris) flowershave a high mucilage content and are used as a remedy for cut wound and dermal infected wounds in iranian folklore medicine. the purpose of this study was to investigate the effect of m. sylvestris cream on the second degree burn injury in rats. materials and methods: fiv...