background the major challenge for a burn team is nosocomial infection, which is known to be responsible for over 50% of burn-related deaths. most studies on infection in burn patients focus on burn wound infection, whereas other nosocomial infections among these patients have not been addressed well. this study attempts to determine three types of nosocomial infections: burn wound, urinary tra...

materials and methods in this study, 90 patients with second-degree burn injuries who were admitted to the yazd burn hospital were randomly divided into three equal groups. in the negative control group, the wounds were covered with sterile vaseline gauze followed by double sterile dry gauze and ultimately bandaged. in the test group, the wounds were covered by an iranian hydrogel sheet (irgel)...

BACKGROND Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. This study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients; their susceptibility pattern to commonly used antibiotics; and the frequency of infections with respect to the durati...

This study aimed to clarify the effects of honey on acute-phase deep burn wounds. Two deep burn wounds were created on mice which were divided into four groups: no treatment, silver sulfadiazine, manuka honey, and Japanese acacia honey. Wound sizes were calculated as expanded wound areas and sampled 30 minutes and 1-4 days after wounding for histological observation. The wound sections were sub...

Dear Editors, We read the article titled ‘Cleansing of wounds by tap water? An evidence-based systemic analysis’ as well as the letter ‘Cleansing of wounds by tap water? Would it be safe to use in developing countries?’ by Huang et al. and Nagoba et al. with great interest (1,2). While we agree with Huang et al. that tap water irrigation helps reduce wound colonisation and infection rates cost-...

"Nubiotics" are a novel class of proprietary protonated nucleic acid-based drugs shown to have potent in vitro antibacterial activities against a number of gram-positive and gram-negative bacteria. These nubiotics are evaluated here for their in vivo therapeutic efficacy for the treatment of burn wound infection caused by Pseudomonas aeruginosa. To achieve this, a burn wound infection model was...

Bacteriophages could be used along with burn wound care products to enhance antimicrobial pressure during treatment. However, some of the components of the topical antimicrobials that are traditionally used for the prevention and treatment of burn wound infection might affect the activity of phages. Therefore, it is imperative to determine the counteraction of therapeutic phage preparations by ...

BACKGROUND For successful wound healing of extensive burn injuries, air circulation around the wound and drainage of wound secretion is inevitable. Therefore, typically extensive burn injuries are treated by using a specifi cally adapted hospital bed (e.g. Clinitron AF). The patient is bedded in a mass of micro glass balls, which are swirled by the application of a strong air current to support...

Polymeric ultra-thin films (nanosheets) possess unique properties that make them suitable materials for various biomedical applications. In our previous study, we assessed the use of an antibiotic (tetracycline, TC)-loaded nanosheet (or "TC-nanosheet") for the treatment of gastrointestinal tissue defects. The nanosheet consisted of three functional layers: layer-by-layer nanosheet as a stable p...