Brucella is an intracellular bacterium that causes the zoonosis brucellosis worldwide. Alveolar macrophages (AM) constitute the main cell target of inhaled Brucella. Brucella thwarts immune surveillance and evokes endoplasmic reticulum (ER) stress to replicate in macrophages via virulence factors. The GntR regulators family was concentrated as an important virulence factor in controlling virule...

Almost 93% of 97 separate patient isolates of Brucella bloodstream infections were recovered within 5 days of incubation by using the BACTEC 9240 continuous-monitoring blood culturing system.

Yersinia enterocolitica O:9 infections were reported in Auvergne in 1988 to 1989, while brucellosis due to Brucella abortus was almost eliminated. The serologic cross-reactions between the two bacteria complicated the diagnosis of brucellosis cases. In 1996, human cases of Yersinia enterocolitica O:9 infection were detected, with a peak incidence of 12 cases. Veterinary surveillance could have ...

Brucellosis, an infectious disease transmitted to humans principally through exposure to contaminated milk products, is endemic to the Middle East [1]. In Egypt, a crosssectional study found that 11% of the population had serological evidence of infection with Brucella spp., while a study of acute febrile illnesses found that 3% of all bacteraemias were caused by the organism [2,3]. Brucella sp...

We report an outbreak of laboratory-acquired Brucella abortus infection originating in the accidental breakage of a centrifuge tube. A total of 12 laboratory workers were infected (attack rate of 31%), with an incubation time ranging from 6 weeks to 5 months. Antibody titers were evaluated weekly in all personnel exposed, allowing the diagnosis of the infection in most cases before the onset of...

INTRODUCTION No cases of human brucellosis caused by Brucella suis has been reported in Spain. METHODS This study involved interviews with the case and his co-workers, inspection of their workplace, checking infection control measures, and typing the Brucella strain isolated in the blood culture. RESULTS Brucella suis biovar 1 strain 1330 was isolated from a patient who worked in a waste tr...

A case was presented with the report of abortion in a jersey crossbred cow about 4 th month of gestational age. Samples were collected from aborted cow and aborted foetus. The samples were found to be negative for Brucella spp., Leptospira spp., and Camphylobacter spp. Cultural and biochemical characters identified as Trueperella pyogenes. Further, Polymerase Chain Reaction (PCR) using gene spe...