BACKGROUND AND PURPOSE Our purpose was to develop a classification scheme and method of presentation of in vivo single-voxel proton spectroscopic data from astrocytomas that most closely match the classification scheme determined from biopsy specimens. Since in vivo proton spectroscopy is noninvasive, it may be an attractive alternative to intracranial biopsy. METHODS Single-voxel spectra wer...

Dysembryoplastic neuroepithelial tumor (DNET) is a recently described, morphologically unique, and surgically curable low grade brain which included in the WHO CNS classification as neuronal mixed glial tumor. It usually seen children young adults. This entity first described by Damas-Duport 1998 non-recurring with an excellent prognosis. We present case of 30 year old female experiencing seizu...

OBJECTIVE To determine the utility of perfusion MR imaging in the differential diagnosis of brain tumors. MATERIALS AND METHODS Fifty-seven patients with pathologically proven brain tumors (21 high-grade gliomas, 8 low-grade gliomas, 8 lymphomas, 6 hemangioblastomas, 7 metastases, and 7 various other tumors) were included in this study. Relative cerebral blood volume (rCBV) and time-to-peak (...

the brain is a rare site for metastasis in most extracranial pediatric solid tumors, including wilm’s tumor. outcome for these patients are generally dismal. very few cases have been reported to have good survival even after therapy. this paper reports a case of stage iv wilm’s tumor with lung metastases in a patient who developed a solitary brain metastasis five months after completion of chem...

Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

Glioma is the most common form of primary brain tumor. Although surgical resection of the tumor may be achieved, recurrence is almost inevitable because of the propensity of gliomas for infiltrative growth far into functionally intact brain tissue. Gliomas are classified into four clinical grades, with glioblastoma multiforme (GBM) being the most aggressive type (World Health Organization [WHO]...

background the anti-inflammatory properties of magnesium sulfate have never been discussed in brain tumor surgeries. objectives this study is aimed to find anti-inflammatory aspects of high dose magnesium sulfate infusion during perioperative period of neurosurgical patients through checking the serial c-reactive protein (crp) blood levels as a biomarker of inflammation. patients and methods si...

acoustic neuromas (an) are schwann cell-derived tumors that commonly arise from the vestibular portion of the eighth cranial nerve also known as vestibular schwannoma(vs) causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. in many cases, the tumor size may remain unchanged for many years following diagnosis, which is typically made by mri. in the majority of cases the tumor is s...

introduction: gamma knife is an instrument specially designed for treating brain disorders. in gamma knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. the tumor is placed at the isocenter and is treated by the emitted gamma rays. therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surroun...

BACKGROUND There is no universally accepted staging system for primary brain tumors wherein prognostication is mainly based on complex composite indices. AIM To develop a simple, pragmatic, and widely applicable grouping/staging system for gliomas, the most common primary brain tumor. MATERIALS AND METHODS An expert neurooncology panel with representation from radiation oncology, neurosurge...