background acoustic trauma is an injury to the hearing mechanisms in the inner ear due to excessive noise. this injury is the most prevalent cause of sensorineural hearing loss in humans, especially from occupational exposure. previous studies have shown the essential role of free radical formation in the inner ear hearing loss caused by acoustic trauma. objectives this study was performed to d...

Objective Among pediatric injury, brain injury is a leading cause of death and disability. To improve outcomes, many developed countries built neurotrauma databank (NTDB) system but there was not established nationwide coverage NTDB until 2009 and there have been few studies on pediatric traumatic head injury (THI) patients in Korea. Therefore, we analyzed epidemiology and outcome from the big ...

Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. The mechanisms for secondary brain injury are not fully understood and successful treatments for traumatic brain injury (TBI) still remain elusive. This study was underta...

Traumatic brain injury is one of the leading causes morbidity and mortality throughout world. Its increasing incidence, in addition to its fundamental role development neurodegenerative disease, proves especially concerning. Despite extensive preclinical clinical studies, researchers have yet identify a safe effective neuroprotective strategy. Following trauma, secondary from molecular, metabol...

patients and methods the study was performed on 40 tbi patients referred to the shahid beheshti hospital of kashan city and 40 normal controls in kashan. traumatic brain injured patients and normal controls were selected by convenience sampling. two groups filled out the demographic sheet, cognitive failures questionnaire (cfq) and meta-cognitions questionnaire 30 (mcq-30). the data were analyz...

OBJECTIVE Patients with traumatic brain injury (TBI) have a high mortality and morbidity. This pilot study was undertaken to identify contributors to outcome in the early management of patients with TBI and to investigate the feasibility of a larger study. METHODS Road trauma patients who died between January 1 and April 30, 2000 were selected from the Alfred Hospital's Intensive Care Traumat...

Introduction: Accurate evaluation of the extent and severity of neurologic injury is a key component in the care of the trauma patient as traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality in trauma victims. EMS assessment of the severity of such injury affects such decisions as need for transfer to a trauma center. Currently, the Glasgow Coma Scale (GCS) is th...

Objective: To observe the effects of the ganglioside (GM1) on Nogo-A expression in cerebral cortex for the rats which have brain trauma, to explore the possible mechanisms of GMl promoting the nerve repair of traumatic brain injury. Methods: SPF SD rats of 100 were randomly divided into four groups: no operation group (n = 10), sham operation group (n = 20), saline model group (n=35), GMI group...