Fewer than 2% of patients with metastatic prostate cancer (pca) develop brain metastases. Autopsy series have confirmed the rarity of brain metastases. When present, brain metastases occur in end stage, once the pca is castrate-resistant and spread to other sites is extensive. Here, we present a rare case of a patient with pca who developed a solitary parenchymal brain metastasis as first site ...

This study relies on knowledge regarding the neuroplasticity of dual-system components that govern addiction and excessive behavior and suggests that alterations in the grey matter volumes, i.e., brain morphology, of specific regions of interest are associated with technology-related addictions. Using voxel based morphometry (VBM) applied to structural Magnetic Resonance Imaging (MRI) scans of ...

Background: Demyelinating events expressed as abnormal thermoregulatory responses are rare, but intractable fever in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is very rarely reported.Case Report: A 56-year-old woman presented with quadriparesis acroparesthesia. During the admission, developed and persisted for 2 days despite administration of high-dose antipyretics...

Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recent work focused on the molecular derangements leading to brain metastases and outlines areas in ne...

introduction: 99mtc-mibi has been proposed for use as an imaging agent for various tumors, including breast cancer, lung cancer, lymphomas, melanomas and brain neoplastic lesions. brain tumors are very common and radiotherapy being major part of treatment following surgery. after radiotherapy, deteriorating clinical status can be due to either radiation necrosis or recurrent tumor. computed tom...

background: the goal of this study was to determine the reliability of tcd in evaluation of vertebrobasilar arteries in comparison with brain mra in patients suffering from acute vertebrobasilar stroke. methods: samples were patients with definite clinical diagnosis of vertebrobasilar stroke. for all patients brain mri, mra and tcd were performed during the first 48 hours of admission. basilar ...

BACKGROUND Brain metastases of gastrointestinal origin are a rare occurrence. Radiation therapy (RT) in the form of stereotactic radiosurgery (SRS) or whole brain radiation therapy (WBRT) is an effective established treatment modality in either the definitive or adjuvant setting. The aim of this study is to assess the long-term clinical outcomes of patients with gastrointestinal (GI) brain meta...

The global pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome 2 (SARS-CoV-2) persists despite the progress vaccination and increased natural immunity. SARS-CoV-2 associated not only with pneumonia distress, but also many symptoms related to central nervous system (CNS), including loss sense taste smell, headache, convulsions, visual disturbances, impa...

Initial rate studies were carried out using solubilized bovine brain hexokinase. Both ATP 4and 0i, y-5'-adenylyl methylene diphosphonate are competitive inhibitors of MgATP 2and mixed inhibitors of the sugar substrate, while N-acetylglucosamine, a competitive inhibitor of fructose, is a mixed inhibitor of MgATP 2. These results are consistent with a random Bi Bi mechanism for the brain enzyme. ...

The adenosine uptake site has been localized in rat brain by an in vitro light microscopic autoradiographic method, using [3H]nitrobenzylthioinosine ( [3H]NBI) as the probe. The binding characteristics of [3H]NBI on slide-mounted sections are comparable to those seen in studies performed on brain homogenates. A very high density of uptake sites occurs in the nucleus tractus solitarius, in the s...