Neurodegenerative diseases (NDs) have become a serious global health problem as the population ages. Traditionally, treatment strategies for NDs included oral and intravenous administration; however, blood–brain barrier (BBB) can prevent drugs from reaching brain, rendering incomplete effect unsatisfactory. Additionally, prolonged or excessive use of that cross BBB damage liver kidney function....

European Society of Radiology (ESR): Imaging is known for its ability to detect and diagnose diseases. What kind of brain diseases can imaging help to detect and diagnose? Miloš Lučić: Actually, there are very few brain diseases that can’t be diagnosed by modern imaging techniques nowadays. Thanks to the extraordinary breakthroughs in imaging technology in the last decades, neuroradiologists ha...

today multinational studies using genome-wide association scan (gwas) for >1000,000 polymorphisms on >100,000 cases with major psychiatric diseases versus controls, combined with next-generation sequencing have found ~100 genetic polymorphisms associated with schizophrenia (scz), bipolar disorder (bd), autism, attention deficit and hyperactivity disorder (adhd), etc. however, the effect size of...

Medicinal plants have attracted global attention due to their high levels of antioxidant components for prohibiting or improving various diseases including brain and memory disorders. This study was designed to investigate if the antioxidant effect of Sidr (Zizyphusspina-christi) extract can help to improve the scopolamine induced impairment of memory in Wistar rats. Animals were randomly...

background: characterizing the mechanical properties of brain tissue is deemed important for developing a comprehensive knowledge of the mechanisms underlying brain diseases. mechanical properties of very soft tissues, such as brain until recently have been attracted the attention of researchers because these tissues do not tolerate mechanical loads. the mechanical properties of brain tissue, h...

The paper presents one of the options for automating evaluation procedures magnetic resonance imaging (MRI) brain in patients suffering from most severe diseases central nervous system (CNS), multiple sclerosis.