By suppressing the expression of genes with essential biological functions, in planta RNAi can negatively affect the development and survival of target pests. As a part of a concerted effort to assess the risks of RNAi transgenic crops on non-target organisms, we developed an in vivo toxicity assay to examine the impacts of ingested dsRNAs incurred to the monarch butterfly, Danaus plexippus (L....

BACKGROUND Carotid-femoral pulse wave velocity (PWV) is a prognostic factor in arterial hypertension. Modification of PWV, apart from blood pressure (BP) lowering seems to be important in the evaluation of antihypertensive drugs. One of the underlying causes arterial stiffening is arterial wall fibrosis. Plasma collagen I metabolites: carboxy (PICP) and amino (PINP) propeptides are considered a...

BACKGROUND Blood pressure (BP) responses to dietary sodium and potassium intervention and cold pressor test vary considerably among individuals. We aimed to identify novel genetic variants influencing individuals' BP responses to dietary intervention and cold pressor test. METHODS AND RESULTS We conducted a genome-wide association study of BP responses in 1881 Han Chinese and de novo genotype...

D.ARDOUIN , BELLETOILE A., CHARRIER D., DALLIER R., DENIS L., ESCHSTRUTH P., GOUSSET T., HADDAD F., LAMBLIN J., LAUTRIDOU P., LECACHEUX A., MONNIER-RAGAIGNE D., RAHMANI A., RAVEL O. SUBATECH, La Chantrerie, 4 rue Alfred Kastler, BP 20722, 44307 Nantes-cedex 3 Observatoire de Paris Station de radioastronomie, 18330 Nançay LESIA, Observatoire de Paris, Section de Meudon, 5 place Jules Janssen, 92...

DEFINITION A relational query language Q is BP-complete if for each relational database D, the set of all relations defined by the queries of Q on D is equal to the set of all first-order definable relations over D. More formally, fix some infinite universe U of atomic data elements. A relational database schema S is a finite set of relation names, each with an associated arity. A relational da...

We sequenced the complete mitochondrial genome of Phalera flavescens. The mitogenome is 15,659 bp in length, including 13 protein-coding genes (atp6, atp8, cox1-3, nad1-6, nad4L, cob), two ribosomal RNAs (rrnS and rrnL), 22 transfer RNAs and an AT-rich region, a putative control region (D-loop). Gene order and orientation were found to be identical to those of other completely sequenced lepidop...

The relative importance of systolic blood pressure (SBP) versus diastolic blood pressure (DBP) in predicting the risk of ischaemic heart disease (IHD) mortality is controversial. We have re-examined SBP compared to D BP and other combinations of SBP and D BP in predicting the risk of IHD mortality in a long-term cohort study oflO,541 men and women in the West of Scotland. During a mean fo...

INTRODUCTION Serum 25-hydroxyvitamin D (25OHD) deficiency (<50 nmol/l or 20 ng/ml) has been associated with increased blood pressure (BP) in observational studies. A paucity of data on this relationship is available in Latin American or child populations. This study investigates the association between 25OHD levels and BP in adolescents at risk for vitamin D deficiency in 2 Peruvian settings. ...

BACKGROUND There are only a few trials for the very elderly population (>79 years). No consensus, which blood pressure (BP) goals and substances should be applied, has been found yet. This survey was undertaken to investigate how octogenarians are treated and attain BP targets in the Swiss primary care. METHODS Data from 4594 hypertensive patients were collected within 7 days. Eight hundred a...