BACKGROUND Difficulties with ambulation in patients with myelomeningocele often lead to physical inactivity, osteoporosis, and subsequent development of pathologic fractures. OBJECTIVE The purpose of this study was to examine bone mineral density and biochemical markers of bone metabolism in patients with myelomeningocele. DESIGN AND METHODS A total of 35 patients between 6 and 19 years of ...

This field study included the whole population of children aged 10-15 years (77 from a 0.19 mg/L F area; 89 from a 3.00 mg/L F area), with similar nutritional, dietary habits and similar ethnic and socioeconomic status. The fluoride concentration in the drinking water, the bone mineral content, the bone density and the degree of dental fluorosis were determined. The left radius was measured for...

BACKGROUND AND PURPOSE Established methods of assessing bone mineral density are associated with additional radiation exposure to the patient. In this study, we aimed to validate a method of assessing bone mineral density in routine multidetector row CT of the lumbar spine. MATERIALS AND METHODS In 38 patients, bone mineral density was assessed in quantitative CT as a standard of reference an...

OBJECTIVE: We aimed to analyze the applicability of a fracture risk assessment tool for the prediction of osteoporotic fractures in middle-aged and elderly healthy Chinese adults. METHODS: A standard questionnaire was administered, and bone mineral density was measured in residents visiting the Dongliu Street Community Health Service Center. Paired t-tests were used to compare the FRAX-based ...

Background Metatarsal fractures, especially of the fifth metatarsal, are common injuries of the foot in a young athletic population, but the risk factors for this injury are not well understood. Dual-energy x-ray absorptiometry (DXA) provides reliable measures of regional bone mineral density to predict fracture risk in the hip and lumbar spine. Recently, sub-regional metatarsal reliability was...

Bone quality describes aspects of bone composition and structure that contribute to bone strength independently of bone mineral density. These include bone turnover, microarchitecture, mineralisation, microdamage and the composition of bone matrix and mineral. New techniques to assess these components of bone quality are being developed and should produce important insights into determinants of...

OBJECTIVE To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN Population based study. SETTING Outpatient clinic for research into osteoporosis. SUBJECTS 178 healthy early postmenopausal w...

STUDY OBJECTIVE To examine the relation between physical activity, calcium intake, and bone mineral content in children. DESIGN Population based, cross sectional study. SETTING Primary schools in Zoetermeer, The Netherlands. PARTICIPANTS Altogether 1359 Dutch boys and girls, aged 7 to 11 years (response rate 88%). MEASUREMENTS Bone mineral content was measured by quantitative roentgen m...

INTRODUCTION Genetic studies of osteoporosis have commonly examined SNPs in candidate genes or whole genome analyses, but insertions and deletions of DNA, collectively called copy number variations (CNVs), also comprise a large amount of the genetic variability between individuals. Previously, SNPs in the APC gene have been strongly associated with femoral neck and lumbar spine volumetric bone ...

OBJECTIVES The association between carbonated beverage consumption and bone mineral density was examined in a community-based cohort of older White women. METHODS One thousand women 44 to 98 years of age had bone mineral density measured at four sites and provided medical and behavioral histories, including type and quantity of carbonated beverages consumed. RESULTS Bone mineral density lev...