Aplastic anemia is a life-threatening condition characterized by the suppression of all hematopoietic lineages in bone marrow. Empty intertrabecular spaces are replaced adipose tissue. With modern MR techniques for assessing fat fraction, it has become possible to capture these changes. The fraction estimated as ratio signal intensity from sum and water signals. Aim study: assess diagnostic val...

Objective: The bone marrow is the primary site for blood cell formation, responsible production and export of red cells, platelets, granulocytes. Pancytopenia a condition characterized by reduction in all three types cellular components peripheral blood, leading to symptoms failure. management prognosis pancytopenia depend on identifying underlying pathology.
 Methods: pathophysiology invo...

Objective(s):To study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. Materials and Methods:Forty New Zealand rabbits were randomly divided into five groups with eight rabbits in each group. For each group, bone defects were generated in the left humerus of four rabbits, and in the right humerus of the other four rabbits. To t...

We describe two fatal cases of low dose methotrexate (MTX) toxicity in patients with psoriasis, emphasizing the factors that exacerbate MTX toxicity. The first patient was a 50-year-old male of psoriasis on intermittent treatment with MTX. After a treatment-free period of six months, he had self-medication of MTX along with analgesic for joint pain for one week which followed ulceration of the ...

In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens. A diagnosis of testicular tumor and associated bone marrow suppression was made by ultrasonography and blood examination, with estrogen blood levels being sever...

anemia is the most common hematologic disorder in patients with ulcerative colitis (uc). in some cases, normochromic anemia results from the presence of chronic disease; however blood loss or malabsorption may lead to an iron deficiency anemia with hypochromic appearance. other rare hematologic manifestations associated with uc include myelodysplastic syndromes and leukemia. several investigato...

Methotrexate is known as a folate antimetabolite. The side effects of methotrexate are not usually seen in low dosages. Here we present patient with inflammatory colitis due to use for psoriasis.A 29 year-old male who was diagnosed psoriasis 1 year ago and started 2 weeks; applied emergency acute abdomen symptoms. According the tests examinations toxicity. observed abdominal pain without surgic...