how to cite this article: taghdiri mm. other experimental therapies in neimann pick diseases. iran j child neurol. 2015 autumn;9:4(suppl.1): 25.   pls see pdf.

objective: demyelination of cns axons occurs under pathological conditions such as multiple sclerosis and spinal cord injuries, but can be repaired by cell therapy. within the cns remyelination can be achieved by transplantation of neural stem cells (nscs). nscs are self-renewing cells that maintain the capacity to differentiate into cns-specific cell types and can differentiate into the three ...

background: in recent years we have successfully adopted an in vitro hepatogenic differentiation of mesenchymal stem cells (mscs). in this protocol the biologically active hepatocyte-like cells were differentiated from the stem cells isolated from either bone marrow or umbilical cord blood (ucb) samples. the aim of the present study was to compare the efficiency of the hepatogenic differentiati...

Mediastinal Myeloid Sarcoma is a rare entity. Here we present case of 28-year-old gentleman, who first presented with mediastinal mass and was clinically considered lymphoblastic lymphoma. He diagnosed initially as having T lymphoma on trucut biopsy. After one month patient Acute myeloid leukemia peripheral smear bone marrow examination confirmed the help flow cytometry. The biopsy slides from ...

BACKGROUND Hepatocellular adenomas are the most common benign liver tumors. They are usually related to oral contraceptive intake. CASE PRESENTATION This case describes a 58-year-old woman admitted to our institution for a hepatic mass incidentally discovered during a routine examination. The patient, who was never on oral contraceptives, was asymptomatic upon admission. She underwent a thoro...

Since the era of tyrosine kinase inhibitor (TKI) therapy, there has been an increase in median survival chronic myeloid leukemia. Nevertheless, nowadays were several cases leukemia that are resistant to first-line TKIs, so second-line TKIs introduced. Assessment therapeutic response was performed using a complete peripheral blood examination, bone marrow aspiration cytogenetic and quantitative ...

Introduction Examination of bone marrow biopsy specimens is a valuable diagnostic procedure in patients with known or suspected lymphoproliferative disorders. ' A bone marrow biopsy specimen may be diagnostic in patients without lymphadenopathy or when there is no conclusive histological evidence from other sites. In some conditions, such as hairy cell leukaemia,2 it is the primary diagnostic p...

One-day-old SPF chicks were inoculated with the Cux-l strain of chicken infectious anemia virus (CIAV), and the clinical development of disease and its macroscopic and microscopic alterations in the thymus and bone marrow, were observed. Tissue sections of thymus and bone marrow were stained using the streptavidin-biotin peroxidase method and examined under light microscope for evaluation of an...

Equine bone marrow analysis is an often underused technique that can provide invaluable diagnostic and prognostic information for horses with quantitative or qualitative abnormalities of blood cells. The primary function of bone marrow is the production of erythrocytes, leukocytes, and platelets. Consequently, abnormalities in the bone marrow are often reflected in the numbers or morphology of ...

BACKGROUND Bone marrow necrosis is a relatively rare entity which has been associated with a poor prognosis. It is most commonly found in patients with neoplastic disorders and severe infections. METHODS The study comprised examination of 5043 bone marrow biopsy specimens performed at the National Cancer Institute, Cairo University, over 7 years period (March 2004-March 2011). It included 5 y...