نتایج جستجو برای: bone injury
تعداد نتایج: 606572 فیلتر نتایج به سال:
Two cases with open, comminuted, axially displaced fractures of the proximal third fourth metatarsal bone were referred to University Equine Hospital Vienna. Due concerns regarding risk injury suspensory ligament and implant infection an open configuration, surgical treatment ostectomy fractured was performed in both cases. Based on telephone follow-up, Case 1 reported be sound no significant r...
Several investigations have demonstrated a precise balance to exist between bone morphogenetic protein (BMP) agonists and antagonists, dictating BMP signaling and osteogenesis. We report a novel approach to manipulate BMP activity through a down-regulation of the potent BMP antagonist Noggin, and examined the effects on the bone forming capacity of osteoblasts. Reduction of noggin enhanced BMP ...
Many reports have revealed the importance of the sympathetic nervous system (SNS) in the control of the bone marrow environment. However, the specific role of neuropeptide Y (NPY) in this process has not been systematically studied. Here we show that NPY-deficient mice have significantly reduced hematopoietic stem cell (HSC) numbers and impaired regeneration in bone marrow due to apoptotic dest...
BACKGROUND AND PURPOSE Bone healing is a complex process influenced by growth factors, cytokines, and other mediators. The regulation of this process is not well understood. In this pilot study, we used microdialysis technology in a critical-size bone defect in rat femurs to determine the feasibility of measuring cytokines and growth factors in the first 24 h after injury. METHODS A 5-mm defe...
Bone injury induces an inflammatory response that involves neutrophils, macrophages and other inflammatory cells. The recruitment of inflammatory cells to sites of injury occurs in response to specific signaling pathways. The CC chemokine receptor type 2 (CCR2) is crucial for recruiting macrophages, as well as regulating osteoclast function. In this study, we examined fracture healing in Ccr2-/...
Abstract Background: Reduction of bone density is some risk factors of falling, injury, or even death in elderly people. The purpose of the present study is investigating the effect of 12 weeks resistance training in water on bone density of elderly women. Methods: Thus 24 old women were selected after medical screening and randomly divided into two groups experimental (12 people, age 65±...
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