نتایج جستجو برای: bone biomarkers

تعداد نتایج: 402955  

Journal: :The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2004

Journal: :AIDS 2016
Ighovwerha Ofotokun Kehmia Titanji Aswani Vunnava Susanne Roser-Page Tatyana Vikulina Francois Villinger Kenneth Rogers Anandi N Sheth Cecile Delille Lahiri Jeffrey L Lennox M Neale Weitzmann

OBJECTIVE Antiretroviral therapy (ART) paradoxically intensifies bone loss in the setting of HIV infection. Although the extent of bone loss varies, it occurs with virtually all ART types, suggesting a common pathway that may be aligned with HIV disease reversal. Using an animal model of immunodeficiency we recently demonstrated that immune activation associated with CD4 T-cell reconstitution i...

2017
Chenguang Li Peizhan Chen Xiaohua Duan Jing Wang Bing Shu Xiaoguang Li Qian Ba Jingquan Li Yongjun Wang Hui Wang

Total 25(OH)D levels were determined to assess bone health in elderly populations; however, the bioavailability of 25(OH)D is regulated by the albumin and vitamin D binding protein (DBP) levels and DBP variations. Whether bioavailable 25(OH)D level is a superior biomarker for vitamin D than total 25(OH)D level regarding the BMD and the bone metabolism were not yet fully understood. With a commu...

2017
Jessica L Kelleher Daniel P Beavers Rebecca M Henderson Dixie Yow Charlotte Crotts Jessica Kiel Barbara J Nicklas Kristen M Beavers

Background To examine the effects of daily weighted vest use during a dietary weight loss intervention, on (a) hip and spine bone mineral density (aBMD), and (b) biomarkers of bone turnover, in older adults with obesity. Methods 37 older (70.1 ± 3.0 years) adults with obesity (BMI=35.3 ± 2.9) underwent a 22 week dietary weight loss intervention (1100-1300 kcal/day) with (Diet+Vest; n=20) or w...

2015
John S. Ji Melinda C. Power David Sparrow Avron Spiro Howard Hu Elan D. Louis Marc G. Weisskopf

BACKGROUND Tremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene. OBJECTIVE We aimed to examine the relationship between lead and tremor, including modification b...

2014
Vincent Goëb Patrice Fardellone Jean Sibilia Frédérique Ponchel

Rheumatoid arthritis (RA) is a chronic inflammatory autoim-mune disease that leads to severe joint destruction with deformity and irremediable disability. Early diagnosis of RA and timely initiation of treatments (synthetic and/or biological disease modifying antirheumatic drugs) are both instrumental to limit joint damage and optimize the functional outcome of patients, according to the well-k...

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