نتایج جستجو برای: bloodstream

تعداد نتایج: 10128  

Journal: :Irish medical journal 2014
M O'Hanlon G Dornikova R Curran M Staunton A Woolhead M Kennedy A Tinsley E Shepherd T Doherty

Bloodstream infection related to a central venous catheter in the intensive care unit is a substantial clinical and economic problem. The aim of the study was to examine the incidence of central line related bloodstream infections and central line associated bloodstream infections in Our Lady of Lourdes Hospital, Drogheda, during a six month period, using an active patient based prospective sur...

Journal: :Cell host & microbe 2011
Changbin Chen Kalyan Pande Sarah D French Brian B Tuch Suzanne M Noble

The mammalian gastrointestinal tract and bloodstream are highly disparate biological niches that differ in concentrations of nutrients such as iron. However, some commensal-pathogenic microorganisms, such as the yeast Candida albicans, thrive in both environments. We report the evolution of a transcription circuit in C. albicans that controls iron uptake and determines its fitness in both niche...

Journal: :Nucleic acids research 1985
J E Feagin D P Jasmer K Stuart

Cytochromes and Krebs cycle enzymes are not detected in bloodstream forms of Trypanosoma brucei but are present in procyclic forms. We have analyzed transcription of mitochondrial sequences which contain the apocytochrome b gene and several other open reading frames (ORFs). Multiple transcripts map to individual DNA sequences located on both DNA strands. Larger low abundance transcripts map to ...

Journal: :Diagnostic microbiology and infectious disease 2018
Haley J Appaneal Aisling R Caffrey Lan Jiang David Dosa Leonard A Mermel Kerry L LaPlante

Pseudomonas aeruginosa is a major cause of healthcare-associated infections and resistance among isolates is an increasing burden. The study purpose was to describe national resistance rates for clinical P. aeruginosa respiratory and bloodstream cultures and the prevalence of multidrug-resistant (MDR) P. aeruginosa within the Veterans Affairs (VA). MDR was defined as non-susceptibility to at le...

Journal: :Memorias do Instituto Oswaldo Cruz 2006
Renata B de Oliveira Aline B M Vaz Rosana O Alves Daniel B Liarte Claudio L Donnici Alvaro J Romanha Carlos L Zani

The natural lignans veraguensin and grandisin have been reported to be active against Trypanosoma cruzi bloodstream forms. Aiming at the total synthesis of these and related compounds, we prepared three 2-arylfurans and eight 2,5-diarylfurans. They were evaluated for their potential as T. cruzi trypanothione reductase (TR) inhibitors as well against the parasite's intracellular (amastigote) and...

2012
Sook-In Jung Jong Hee Shin Hyun-Jung Choi Min-Young Ju Soo-Hyun Kim Wee Gyo Lee Yeon-Joon Park Kyungwon Lee

The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4...

Journal: :JAMA 1999
D L Veenstra S Saint S Saha T Lumley S D Sullivan

CONTEXT Central venous catheters impregnated with chlorhexidine and silver sulfadiazine have recently been introduced for the prevention of catheter-related infections. However, there remains some uncertainty regarding the efficacy of these catheters because of conflicting reports in the literature. OBJECTIVE To evaluate the efficacy of chlorhexidine-silver sulfadiazine-impregnated central ve...

Journal: :Annals of the Academy of Medicine, Singapore 2008
Thean Yen Tan Ai Ling Tan Nancy W S Tee Lily S Y Ng

INTRODUCTION Worldwide, Candida albicans is the most common Candida species implicated in bloodstream infections. However, the proportion of non-albicans bloodstream infections is increasing. Fluconazole resistance is known to be more common in non-albicans species, but is also reported in C. albicans. This retrospective study was performed to determine the species epidemiology of Candida blood...

Journal: :Critical care medicine 2003
Marco Ranucci Giuseppe Isgrò Pier Paolo Giomarelli Marco Pavesi Aldo Luzzani Iolter Cattabriga Manuela Carli Paolo Giomi Antonio Compostella Antonio Digito Valerio Mangani Vito Silvestri Enzo Mondelli

OBJECTIVE To evaluate a new antimicrobial treatment for central venous catheters in comparison with a traditional treatment, by assessing the catheter colonization and catheter-related bloodstream infection rates in two groups of patients. DESIGN Multiple-center, prospective randomized study. SETTING The medical and surgical departments of ten institutions. PATIENTS Patients requiring a c...

2014
Evelyn D. Olthof Michelle W. Versleijen Getty Huisman–de Waal Ton Feuth Wietske Kievit Geert J. A. Wanten

BACKGROUND AND AIMS Patients on home parenteral nutrition (HPN) are at risk for catheter-related complications; mainly infections and occlusions. We have previously shown in HPN patients presenting with catheter sepsis that catheter locking with taurolidine dramatically reduced re-infections when compared with heparin. Our HPN population therefore switched from heparin to taurolidine in 2008. T...

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