The hyperbaric oxygen inhaled at the pressure od 2-3 atmospheres raises considerably the blood concentration of the gas, which becomes sufficient for tissular needs sometimes without soliciting hemoglobin intervention. This makes possible the survival of some tissues insufficiently supplied with blood. We forecast therapeutical indications in diabetic retinopathy, hypertensive retinopathy, reti...

CONTEXT There is no true substitute for the many functions of human red blood cells, and synthetic products will not replace the need for blood donation in the foreseeable future. Hemoglobin-based oxygen carriers have many characteristics that would serve as a useful adjunct to red cells in clinical settings. Over time, these technologies have the potential to dramatically reshape the practice ...

Background Effective health care delivery to the majority of perinatally exposed infants is hampered by lack of access to accurate HIV diagnosis in infancy. Polymerase chain reaction is the most sensitive test to diagnose HIV-1 infection in children born to HIV seropositive mothers. The purpose of this study was to assess the feasibility and accuracy of using dried blood spot (DBS) technology i...

Automated laboratories analyze thousands of blood tests every day. Some samples can become contaminated by improper collection, producing incorrect results. Identification of such samples is critical and requires a labor intensive expert review. In our previous work, we demonstrated a useful machine learning approach to automated detection, but a severe class imbalance in the dataset led to uns...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...

The fetus is more susceptible than the adult to the effects of certain carcinogens, such as polycyclic aromatic hydrocarbons (PAH). Nutritional factors, including antioxidants, have been shown to have a protective effect on carcinogen-DNA adducts and cancer risk in adults. We investigated whether the effect of prenatal airborne PAH exposure, measured by personal air monitoring during pregnancy,...

Drunk driving is, in Canada, the leading cause of death on the roads. To reduce the number of drinking and driving incidences, new technologies were developed to accurately measure blood alcohol concentration (BAC) and overcome the limitations of current alcohol measuring technologies. In this research, a non-contacting, non-invasive in-vehicle alcohol biosensor is developed using laser-based W...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...