AIMS Vitamin C (ascorbic acid) is a powerful antioxidant but there is limited information on its ability to prevent LDL oxidation and its interaction with other natural antioxidants in vivo. We assessed the effect of 4 weeks pharmacological supplementation with vitamin C 1 g day(-1) on copper induced LDL oxidation and lipid peroxidation. METHODS Blood samples were obtained at baseline and at ...

Cadmium (Cd) is a highly toxic heavy metal, wide occupational and an environmental pollutant, affecting human health. Probiotics especially lactic acid bacteria (LAB) have the capacity to bind, remove and to decrease tissue cadmium levels. The objective was to evaluate the potency of Cd binding capacity, antioxidative properties of probiotic bacteria against cadmium in vitro and its probable de...

Introduction: The etiology of myoglobinuric acute kidney injury involves oxidative brought on by the Fenton reaction and myoglobin redox cycle. Renal tubules may be harmed, lipid peroxidation compounds with vasoconstrictor characteristics produced. N-acetylcysteine (NAC) is an antioxidant shown to improve renal microcirculation have protective effects in various models damage. aim study was dem...

conclusions the results of our study proposed that there is a loss or inactivation of antioxidant factors, coupled with increased lipid peroxidation during the procedure of hd, possibly through the dialyzer membrane, with probable consequences on the severity of illness. results the sod, gpx and cat were decreased after hd (p < 0.05). also, frap was shown to decrease after hd (p < 0.05). howeve...

background: medicinal plants with biologically active components such as antioxidant and antidiabetic are useful sources of novel therapeutics. in iran, traditionally believed that the aqueous extract of berberry fruit (berberis integerima f.) improved health, especially in people with diabetes. objective: in this study, in vitro phytochemical and antioxidant activities of b. integerrima and b....

Ferula gummosa Boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. There are also several reports on antioxidant effects of these compounds. The aim of this study was to investigate the effect of daily administration of F. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. Twenty four Wistar rats were randomly divided...

As a consequence of enhanced production of oxygen free radicals, lipid peroxidation leads to the degradation of membrane lipids and disturbances of membrane permeability. Lipid peroxidation increases under stress conditions such as hypoxia, ischemia or acidosis as well as in metabolic diseases, e.g. diabetes mellitus. We have shown that subcomatous doses of insulin (6.0 IU/kg) significantly inc...

background: imbalances between the oxidant–antioxidant status have been implicated in the pathogenesis of several diseases, including cancer. the aim of this study was to evaluate the extent of lipid peroxidation and antioxidants in the tissue samples of oral squamous cell carcinoma (oscc) patients of different clinical stages in comparison with the healthy controls. materials and methods: a ca...