Two-dimensional thin-layer chromatography was used to resolve cyclophosphamide metabolites present (a) in blood and urine of cyclophosphamide-treated rats and (b) after incuba tion of cyclophosphamide with hepatic microsomes, a hepatic 9000 X g supernatant fraction, or a model oxygenase system. Incubation of cyclophosphamide with rat hepatic microsomes yielded a single metabolite (aldophosphami...

different medicinal plants have been used in animal and poultry nutrition in last decade. it seems that there are some potential to these medicinal plants to replace with common antibiotics. licorice root (glycyrrhiza glabra) is a medicinal plant that extensively was used in different studies. in the present study, the effect of dietary addition of licorice root on performance and blood energy ...

Blood plasma is the most popularly used sample matrix for metabolite profiling studies, which aim to achieve global metabolite profiling and biomarker discovery. However, most of the current studies on plasma metabolite profiling focused on either the polar metabolites or lipids. In this study, a comprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar met...

The present investigation includes the blood biochemical alterations in chronic (30 days) exposure of airbreathing fish, Clarias batrachus (Linn.) induced by sublethal concentration (2.46 mg/L) inorganic herbicide, glyphosate. Significant changes were observed properties form hyperglycemia, hypoproteinemia and hypercholesterolemia. study therefore points towards a severe metabolic dysfunction r...

Endotoxemia in bitches with pyometra can cause severe systemic effects directly or via the release of inflammatory mediators. Plasma endotoxin concentrations were measured in ten bitches suffering from pyometra with moderately to severely deteriorated general condition, and in nine bitches admitted to surgery for non-infectious reasons. Endotoxin samples were taken on five occasions before, dur...