background: cytogenetic tests are usually used for diagnosing predisposed individuals to cancer by determining their lymphocyte radiosensitivity. objective: to determine the potential role of radiosensitivity in predisposition of prostate cancer by comparing lymphocyte radiosensitivity of prostate cancer patients with healthy donors. materials and methods: the blood samples of 10 prostate cance...

Introduction: Early diagnosis of gastric cancer is the best solution for reversing cancer and curing patients. So far, gastric cancer is diagnosed in late stages due to misinterpretation of symptoms or absence of specific symptoms. Highly sensitive and selective detection methods for biomarkers are needed for early detection. Methods: This paper proposed a new fast screening method, based on t...

Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide, and its occurrence can be ascribed to genetic susceptibility. Mitochondrial DNA 4977-bp (mtDNA 4977), as the most described mtDNA deletion, has been long proposed to be involved in various types of cancers. However, a few studies on mtDNA 4977-bp deletion in Iranian patients with CRC have been reported. The cu...

Introduction: Early diagnosis and appropriate treatment is required in esophageal cancer due to its invasive nature. The aim of this study was to evaluate early post-esophagectomy complications in patients with esophageal cancer who received neoadjuvant chemoradiotherapy (NACR).   Materials and Methods: This randomized clinical trial was carried out between 2009 and 2011. Patients with lower-th...

Introduction . Researchers in the field of oncology have a significant interest role microorganisms development malignant neoplasms. Aim To study levels 2-heptyl-3-hydroxy-4-quinolone (PQS) and 2-heptyl-4-quinolone (HHQ) produced by Pseudomonas aeruginosa blood patients with lung cancer to analyze relation between their changes level immunoglobulins vascular endothelial growth factor (VEGF) can...

Over 80% of human cancers originate from the epithelium, which covers outer and inner surfaces organs blood vessels. In stratified bottom layers are occupied by stem stem-like cells that continually divide replenish upper layers. this work, we study spread premalignant mutant clones cancer initiation in epithelium using biased voter model on stacked two-dimensional lattices. Our main result is ...

Background: This study aimed to estimate peripheral blood lymphocyte subsets and programmed death receptor-1 positive (PD-1+) proportions of T cells, their impact on progression free survival (PFS) radiological response in lung cancer.

dendritic cells (dcs) are antigen presenting cells with unique capability to take up and process antigens in the peripheral blood and tissues. they subsequently migrate to draining lymph nodes where they present these antigens and stimulate naive t lympho-cytes. during their life cycle, dcs go through two maturation stages and are referred to as immature and mature cells, respectively. while im...