BACKGROUND Treatment with vitamin K antagonists (coumarins) is associated with an increased risk of bleeding. Because use of selective serotonin reuptake inhibitors (SSRIs) is also associated with an increased risk of bleeding, we assessed the odds ratio (OR) of abnormal bleeding associated with SSRI use in users of the coumarins acenocoumarol or phenprocoumon and compared this with the OR of b...

BACKGROUND & AIMS Although sclerotherapy is the current standard therapy for bleeding esophageal varices, the best method for initial control is unclear. The aim of this meta-analysis was to compare the efficacy and toxicity of somatostatin and vasopressin in short-term treatment of hemorrhage from esophageal varices. METHODS Using MEDLINE, all randomized trials comparing somatostatin with va...

BACKGROUND Factor V deficiency is a rare autosomal recessive coagulation disorder. Awareness of presenting features and management is important to avoid bleeding complications associated with mortality and neurodisability. CASE PRESENTATION A 6-day-old Pakistani boy was admitted with bleeding from the left nipple. His parents were first cousins. A coagulation screen showed a prothrombin time ...

AIM The Child Pugh and MELD are good methods for predicting mortality in patients with chronic liver disease. We investigated their performance as risk factors for failure to control bleeding, in-hospital overall mortality and death related to esophageal variceal bleeding episodes. METHODS From a previous collected database, 212 cirrhotic patients with variceal bleeding admitted to our hospit...

  SUMMARY Bleeding of esophageal varices have a high mortality rate, and medical management is usualy unsuccessful. Surgical methods such as vascular ligation or shunting are expensive. High risk procedures with high mortality. Endoscopic sclerotherapy was applied in 104 patients with acute bleeding of esophageal varices during a period of 5 years in a prospettive and retrospective study. Th...

A 78-year-old woman, on rivaroxaban medication because of atrial fibrillation, was referred to our department with upper gastrointestinal bleeding. Emergency esophagogastroduodenoscopy (EGD) revealed multiple duodenal diverticula with oozing bleeding from inside a large diverticulum near the papilla (●" Fig.1 and●" Fig.2). Because of the location, clips were not applicable, hence injection of e...

*Financial sponsoring – none Contrast barium enema is a 60-200% solution of barium sulphate, administered rectally. It is used not only in the diagnostics of colorectal diseases, but also as a therapeutic option in case of intussusception or treatment of lower gastrointestinal tract bleeding. The latter indication raises most controversies amongst surgeons. Opponents argue that 7080% of cases o...

BACKGROUND/AIMS This study was performed to determine whether low-dose aspirin and/or clopidogrel can induce gastrointestinal bleeding and gastroduodenal mucosal injury. METHODS A total of 387 patients who underwent coronary angiography at Seoul National University Bundang Hospital were assigned to one of three antiplatelet treatment groups: (1) control, (2) 100-mg enteric coated aspirin, and...

Background. Recombinant factor VIIa has been in use for some time to control bleeding in persons with hemophilia. In the present study we describe our experience with the use of a commercial form of recombinant factor VIIa, NovoSeven(R) (Novo Nordisk, Denmark), to control perioperative bleeding in the course of total knee replacement on a patient who, though not hemophiliac, had a very low tole...