Polyphenols have attracted attention for their anti-inflammatory, antidiabetic, and anticancer properties. Due to the antioxidant anti-inflammatory potential of these molecules, they are also proposed as a therapeutic tool prevent complications cancer decrease secondary effects conventional chemotherapeutic drugs. Nonetheless, polyphenols such flavonoids phenolic acids low bioavailability, high...

When analyzing large complex protein biopharmaceuticals, ion-pairing agents imparting low pH are widely used as mobile phase additives to improve the chromatographic performance. However, one of most effective in RPLC and HILIC, trifluoroacetic acid (TFA), is known a strong suppressor MS signal limits its use hyphenated techniques. In this study, we evaluated wide range acidic find alternatives...