Antifreeze (glyco) proteins AF(G)Ps are potent ice recrystallization inhibitors, which is a desirable property to enhance cryopreservation of donor tissue/cells. Here we present the rational synthesis of a new, biomimetic, ice-recrystallization inhibiting polymer derived from a cheap commodity polymer, based on an ampholyte structure. The polymer is used to enhance the cryopreservation of red b...

objective(s): the introduction of nucleic acids into cells for therapeutic objectives is significantly hindered by the size and charge of these molecules and therefore requires efficient vectors that assist cellular uptake. for several years great efforts have been devoted to the study of development of recombinant vectors based on biological domains with potential applications in gene therapy....

Illisimonin A is a new sesquiterpene isolated from Illicium simonsii, and it possesses novel 5/5/5/5/5 pentacyclic skeleton. The tricyclic skeleton of illisimonin A, tricyclo[5.2.1.01,5]decane, presumed to be biosynthesized allo-cedranes via skeletal rearrangement. Herein, we report the concise synthesis highly oxidized by an intramolecular Diels–Alder reaction using ortho-benzoquinones demonst...

biomimetic method was used to apply hydroxyapatite (ha) coating onto ti6al4v cylinders. this process is a physicochemical method in which a substrate is soaked in a solution simulating the physiological conditions, for a period of time enough to form a desirable layer of the calcium phosphate on the substrate. in the present study, specimens were soaked in 5, 10 m solutions of naoh at temperatu...

Cell membranes are dynamic structures found in all living organisms. There have been numerous constructs that model phospholipid membranes. However, unlike natural membranes, these biomimetic systems cannot sustain growth owing to an inability to replenish phospholipid-synthesizing catalysts. Here we report on the design and synthesis of artificial membranes embedded with synthetic, self-reprod...

Compartmented Bienzyme Biocatalysts Biomimetic mineralization and slow seed-induced nucleation strategy enables the synthesis of compartmented bienzyme system based on core-shell [email protected] in aqueous solution. can be accurately localized into shell core with uniform distribution. The optimization pore structure positional assembly provides a guidance for preparing efficient multi-enzyme...

Molecular imprinting is a mature and appealing technology to obtain highly selective recognition sites created within polymeric network, having other important features such as robustness cost effectiveness. The applications of molecularly imprinted polymers (MIPs) are vast, but there continuous particular interest in their integration into sensing devices. MIPs possess remarkable properties te...

In this review, we briefly introduce our efforts to reconstruct cellular life processes by mimicking natural systems and the applications of these systems to energy and environmental problems. Functional units of in vitro cellular life processes are based on the fabrication of artificial organelles using protein-incorporated polymersomes and the creation of bioreactors. This concept of an artif...

Hydrogels are biomimetic materials widely used in the area of biomedical engineering and biosensing. Ferrogels (FG) are magnetic composites capable of functioning as magnetic field sensitive transformers and field assisted drug deliverers. FG can be prepared by incorporating magnetic nanoparticles (MNPs) into chemically crosslinked hydrogels. The properties of biomimetic ferrogels for multifunc...

Monensin A is a commercially important natural product isolated from Streptomyces cinnamonensins that is primarily employed to treat coccidiosis. Monensin A selectively complexes and transports sodium cations across lipid membranes and displays a variety of biological properties. In this study, we evaluated the Jacobsen catalyst as a cytochrome P450 biomimetic model to investigate the oxidation...