I n t e r v e n t i o n Patients were allocated to bed rest (n = 84), physiotherapy (n = 83), or continuation of ADLs (n = 83). Bed rest could be done at home or in the hospital and lasted 7 days. Physiotherapy sessions were scheduled twice weekly for 4 to 8 weeks and involved segmental mobilization, disc unloading and loading exercises, and hydrotherapy. Patients in the continuation-of-ADLs gr...

For many years, average bed occupancy level has been the primary measure that has guided hospital bed capacity decisions at both policy and managerial levels. Even now, the common wisdom that there is an excess of beds nationally has been based on a federal target of 85% occupancy that was developed about 25 years ago. This paper examines data from New York state and uses queueing analysis to e...

Bed bug (Cimex lectularius L.) infestations are currently controlled by a variety of non-chemical and chemical methods. There have been few studies on the comparative effectiveness of these control techniques. We evaluated three bed bug management strategies in an apartment building: (1) non-chemical methods only (n = 9); (2) insecticides only (n = 6); and (3) integrated pest management includi...

The potential for loss of bone mineral mass due to space flight was recognized by space scientists even before man's first venture into micro-gravity. Early life science studies in both the U.S. and Russian space programs attempted to measure the effects of reduced gravity on skeletal homeostasis, and these measurements have become more sophisticated with time. Bone-related measurements have ty...

The International Space Station ISS offers the opportunity for physiological long-term observations in microgravity in awake animals. The 3-month period of experimentation favours heredity, development and physiological adaptation as scientific fields that can profit from those longterm exposures to microgravity. However, the most complicating problems are (i) the lack of proper animal habitats...

The pharmacokinetics of ibuprofen were studied under microgravity (µG) conditions and compared with those at normal gravity (1G) in humans. Six healthy human volunteers were given 600 mg oral dose ibuprofen during 1-day simulated µG antiorthostatic bed rest position, then at normal position (1G) in a sequential design with 7 days washout time. Saliva and plasma samples were obtained up to 8 hou...

Muscle biopsy has long been expected to be replaced by noninvasive biomarkers with diagnostic value and prognostic applications for muscle atrophy. Growing evidence suggests that circulating microRNAs (miRNAs) could act as biomarkers for numerous pathophysiological statuses. In the present study, our results showed that the serum levels of six muscle-specific miRNAs (miR-1/23a/133/206/208b/499)...