BACKGROUND Mesoporous bioactive glasses (MBGs) are very attractive materials for use in bone tissue regeneration because of their extraordinarily high bone-forming bioactivity in vitro. That is, MBGs may induce the rapid formation of hydroxy apatite (HA) in simulated body fluid (SBF), which is a major inorganic component of bone extracellular matrix (ECM) and comes with both good osteoconductiv...

The sim fruit (Rhodomyrtus tomentosa) has long been used in folk medicine to treat diarrhoea, dysentery, and to boost the immune system. The purpose of this work was to determine its phenolic profile and to evaluate the changes of content during maturation, as well as the variations induced by environmental conditions. Using HPLC-ESI-HR-MS, 19 phenolic compounds (PCs) were tentatively character...

Abstract — Fe2O3 substituted 45S5 bioactive glasses were prepared. Glass derived Bioactive Glass ceramics were obtained through controlled crystallization of bioactive glasses. Nucleation and crystallization regimes were determined by the parameters obtained from differential thermal analysis (DTA) of bioactive glasses. The formed crystalline phases in bioactive glass ceramics were identified u...

Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of years as a remedy for a variety of ailments. The main component of S. marianum fruit extract (silymarin) is a flavonolignan called silybin, which is not only the major silymarin element but is also the most active ingredient of this extract, which has been confirmed in various studies. This compound belongs...

Bioactive compounds are secondary metabolites synthesized by plants for maintaining homeostasis; however, they also modulate metabolic processes and demonstrate valuable effects in the human body. The fig was cherished as food its pharmaceutical properties. presence of a wide range biologically active such carotenoids, flavonoids, phenols, vitamin C is obligated their functional properties well...

the purpose of this research was to study the antimicrobial activities of the endophytic fungi from sesbania grandiflora (l.) pers. the endophytic fungi were isolated from branches and leaves of sesbania grandiflora (l.) pers., and sixty nine isolates were obtained. all isolates were screened for antibacterial and antifungal activities. the indicator organisms were 4 bacteria including staphylo...

background and objectives: entomopathogenic nematodes, belonging to the family heterorhabditis and steinernematidae, are reported to be symbiotically associated with specific bacteria and the secondary metabolites produced by these bacteria possess antimicrobial activity. in this study, bacteria were isolated from nematodes belonging to the family rhabditidae, and the antimicrobial activity was...

BACKGROUND Endophytic fungi, present mainly in the Ascomycota and Basidiomycota phyla, are associated with different plants and represent important producers of bioactive natural products. Brazil has a rich biodiversity of plant species, including those reported as being endemic. Among the endemic Brazilian plant species, Vellozia gigantea (Velloziaceae) is threatened by extinction and is a pro...

In the past decade, tissue engineering-based bone grafting has emerged as a viable alternative to biological and synthetic grafts. The biomaterial component is a critical determinant of the ultimate success of the tissue-engineered graft. Because no single existing material possesses all the necessary properties required in an ideal bone graft, our approach has been to develop a three dimension...

background: woodfordia fruticosa is used traditionally as antidysenteric compound for fodder animals. stem and flower extracts are previously flourished for their antibacterial activity. leaves are also equally important, which are preliminary screened for their bioactive components in present study. objective: evaluation of antibacterial activity of leaves of w. fruticosa and detection of thei...