نتایج جستجو برای: binding cassette transporter
تعداد نتایج: 464028 فیلتر نتایج به سال:
Adenosine triphosphate-binding cassette efflux transporters are highly expressed at the blood-brain barrier and actively hinder passage of harmful compounds, thereby maintaining brain homoeostasis. Since, adenosine triphosphate-binding cassette transporters drive cellular exclusion of potential neurotoxic compounds or inflammatory molecules, alterations in their expression and function at the b...
We report on the functional characterization of GlnPQ, an ATP-binding cassette transporter with four extracytoplasmic substrate-binding domains. The first predicted transmembrane helix of GlnP was cleaved off in the mature protein and most likely serves as the signal sequence for the extracytoplasmic substrate-binding domains. Deletion analysis showed that the substrate-binding domain, in the p...
The ABCB8 is one of the members under ABCB subfamily ATP-Binding Cassette (ABC) transporter which possess ability in regulating intracellular iron and heme transport. loss function mutation gene leads to accumulation cell highly toxic human. However, information regarding expression regulation this remains scarce. Hence, objectives project are determine transcription factors binding site (TFBS)...
Candida glabrata is the second most common species causing candidiasis. C. glabrata can also readily acquire resistance to azole drugs, complicating its treatment. Here we add to the collection of disruption markers to aid in genetic analysis of this yeast. This new construct is marked with a nourseothricin resistance cassette that produces an estrogen-activated form of Cre recombinase in a met...
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