The in-vitro effects of new quinolones and oral cephem antibiotics in various combinations on 26 strains of clinically isolated Serratia marcescens were assessed. The in-vitro activities of ofloxacin and ciprofloxacin in combination with either cefpodoxime or cefcamate were evaluated by the chequerboard titration method. These combinations showed synergistic and additive effects against most of...

Article history: Received 20 December 2014 Received in revised form 20 January 2015 Accepted 16 February 2015 Available online 23 February 2015 QTL IciMapping is freely available public software capable of building high-density linkage maps and mapping quantitative trait loci (QTL) in biparental populations. Eight functionalities are integrated in this software package: (1) BIN: binning of redu...

Vanillin, a food additive, has been evaluated as a potential agent to treat sickle cell anemia. Earlier studies indicated that vanillin had moderate antisickling activity when compared with other aldehydes. We have determined by high performance liquid chromatography that vanillin reacts covalently with sickle hemoglobin (HbS) both in solution and in intact red blood cells. Hemoscan oxygen equi...

In this paper we present a novel approach to quantifying genetic architecture that combines recombinant inbred lines (RIL) with line cross analysis (LCA). LCA is a method of quantifying directional genetic effects (i.e. summed effects of all loci) that differentiate two parental lines. Directional genetic effects are thought to be critical components of genetic architecture for the long term re...

effects of summer savory (satureja hortensis l.) dry powder (ssdp) and essential oil (sseo) on performance, ruminal fermentation and blood metabolites were assessed using 20west azerbaijan native kids (16±1.94 kg initial live weight) in a random block design with 5 treatments (4 replicates per treatment) over a 13-week period. treatments were: i) basal diet without additive (control), ii): basa...

Lod scores provide a method to unify linkage tests based on identity by descent and identity in marker state while permitting selection of the most informative individuals through their disease-related phenotypes and markers in relatives. After parametric lods are reviewed, a nonparametric approach that depends on a single logistic parameter beta is introduced. Lods for parents tested or unknow...

Feature transformation is an important process following feature extraction for improving classification performance. It has been frequently addressed in the kernel-based framework utilizing non-linear kernel functions, and the additive kernel equipped with explicit feature mapping works as efficient and effective (non-linear) feature transformation. The kernel functions, however, are defined i...

Despite its importance to agriculture, the genetic basis of heterosis is still not well understood. The main competing hypotheses include dominance, overdominance, and epistasis. NC design III is an experimental design that has been used for estimating the average degree of dominance of quantitative trait loci (QTL) and also for studying heterosis. In this study, we first develop a multiple-int...