BACKGROUND Immunological test systems for diagnostics of type I hypersensitivity involve the following types of antigens: whole allergen extracts, individual highly purified proteins and their recombinant analogues. The goal of this study was to compare the results obtained with whole allergen extracts (birch pollen, cat dander, and timothy grass pollen) and their respective recombinant protein...

BACKGROUND Trees belonging to the order of Fagales show a distinct geographical distribution. While alder and birch are endemic in the temperate zones of the Northern Hemisphere, hazel, hornbeam and oak prefer a warmer climate. However, specific immunotherapy of Fagales pollen-allergic patients is mainly performed using birch pollen extracts, thus limiting the success of this intervention in bi...

BACKGROUND Dendritic cells (DCs) play an important role in the induction and regulation of adaptive immune responses by polarizing T-helper (Th) cells. In allergic disease this response is dominated by Th2 cells. It is still unclear whether the activation of Th cells by DCs in atopic individuals is allergen specific. METHODS Monocyte-derived DCs (MoDCs) obtained from polysensitized patients w...

Pada penelitian ini dilakukan sintesis TiO2 dengan metode hidrotermal dimana pelarut yang digunakan adalah campuran cairan ion 1-butil-3-metil imidazolium klorida (BMIM Cl) dan air perbandingan 3:7 v/v. Cairan 1- butil-3-metil imidazol disintesis prekursor metil klorobutana kemudian dikarakterisasi menggunakan NMR 43 MHz. telah BMIM Cl : (3:7 v/v) XRD, SEM, UV-Vis/DR BET serta dibandingkan hasi...