s changizi ashtiyani department of physiology, arak university of medical sciences, arak, iran tel & fax: +98 – 861 – 4173526 a zarei 2- department of biology, abadeh branch, islamic azad university s taheri 3- staff of research deputy, arak university of medical sciences a rezaei 4- department of physiology, islamic azad university of arsanjan m golshan 5- department of shiraz university of medical sciences r ghafarzadegan 6- pharmacognosy & pharmaceutics department of medicinal plants research center, institute of medicinal plants, acecr

mohsen imenshahidi department of pharmacodynamy and toxicology, pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran reza qaredashi department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran mahmoud hashemzaei department of pharmacology and toxicology, school of pharmacy, zabol university of medical sciences, zabol, ir iran hossein hosseinzadeh pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran; pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran. tel: +98-5118819042, fax: +98-5118823251

Júlia Morais Fernandes Juliana Félix-Silva Lorena Medeiros da Cunha Jacyra Antunes dos Santos Gomes Emerson Michell da Silva Siqueira Luisa Possamai Gimenes Norberto Peporine Lopes Luiz Alberto Lira Soares Matheus de Freitas Fernandes-Pedrosa Silvana Maria Zucolotto

Inés Ibáñez John A Silander Adam M Wilson Nancy LaFleur Nobuyuki Tanaka Ikutaro Tsuyama