Gallnut water extract (GWE) enriches 80~90% of gallnut tannic acid (TA). In order to study the biodegradation of GWE into gallic acid (GA), the LHS-1 strain, a variant of Aspergillus niger, was chosen to determine the optimal degradation parameters for maximum production of GA by the response surface method. Pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS) was first applied to appraise...

A novel series of carbamothioylamino-benzene-sulfonamide-thiophene-carboxylates 4a-c and thieno[3,2-d]pyrimidin-2-yl-amino-benzene-sulfonamides 5a-c were synthesized in a series of synthetic steps and were used as key intermediates for the synthesis of thienotriazolopyrimidine-benzene-sulfonamide derivatives 6a-c and 7a-c. Thieno[3,2-d]pyrimidinones (8 and 9) were also prepared. Compound 9 was ...

an efficient method for the friedel–crafts acylation of a wide range of aromatic compounds in good to excellent yields under solvent-free conditions, using iron zirconium phosphate (zpfe) was investigated. the catalyst is easy to prepare and shows interesting catalytic properties. the catalyst was characterized by some instrumental techniques such as xrd, icp-oes, sem and tem. a wide variety of...

Palladium-catalyzed aerobic oxidative cross-couplings of indoles and benzene have been achieved by using 4,5-diazafluorene derivatives as ancillary ligands. Proper choice of the neutral and anionic ligands enables control over the reaction regioselectivity.

A highly stable supramolecular helical structure was formed by the self-assembly of novel C6-symmetric hydrogen-bonded discotic molecules, hexakis(phenylethynyl)benzene derivatives with chiral alanine parts, and exhibited orange excimer emission with a large Stokes shift.

Dibenzofuran (DBF) are typical heterocyclic aromatic compounds (O-HETs), which can coexist with polycyclic hydrocarbons (PAHs) in combustion and pyrolysis conditions. In this review, Emphasis has already been placed on the reports synthesis of dibenzofuran derivatives possessing anti-bacterial activities. It is not a comprehensive discussion all such compounds, but instead intended to illustrat...

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

parameters and multiple regression analysis. The variation in the activity of N-(ca-substituted benzyl) derivatives was shown to be related parabolically with variation in the steric dimension of the substituents. The greater the hydrophobicity of substituents is, the greater the activity is. The variation in the steric dimension of the benzene ring substituents was responsible for the activity...

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

Chiral hydroxyl monophosphane 3 [(2S,3S,4S,5S)-3,4-dihydroxy-2, 5-dimethyl-1-phenylphospholane] and bisphospholanes 5a [1,2-bis[(2S, 3S,4S,5S)-3,4-dihydroxy-2,5-dimethylphospholanyl]benzene] and 5b [1, 2-bis[(2S,3S,4S,5S)-2,5-diethyl-3,4-dihydroxyphospholanyl]benzene] were synthesized from readily available D-mannitol in high yields. Strategies for protection and deprotection of OH-groups in th...